Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ-RelB |
Location | 4951924..4952467 | Replicon | chromosome |
Accession | NZ_AP025281 | ||
Organism | Aliamphritea hakodatensis strain PT3 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | PCI15_RS22495 | Protein ID | WP_271272102.1 |
Coordinates | 4951924..4952196 (-) | Length | 91 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | PCI15_RS22500 | Protein ID | WP_271272103.1 |
Coordinates | 4952189..4952467 (-) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PCI15_RS22480 | 4947293..4947952 | + | 660 | WP_271272099.1 | ureidoglycolate lyase | - |
PCI15_RS22485 | 4948317..4948988 | + | 672 | WP_271272100.1 | BRCT domain-containing protein | - |
PCI15_RS22490 | 4949566..4951713 | - | 2148 | WP_271272101.1 | transporter substrate-binding domain-containing protein | - |
PCI15_RS22495 | 4951924..4952196 | - | 273 | WP_271272102.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
PCI15_RS22500 | 4952189..4952467 | - | 279 | WP_271272103.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
PCI15_RS22505 | 4952964..4953269 | - | 306 | WP_271272104.1 | 4a-hydroxytetrahydrobiopterin dehydratase | - |
PCI15_RS22510 | 4953447..4955108 | - | 1662 | WP_271272105.1 | BCCT family transporter | - |
PCI15_RS22515 | 4955265..4956041 | - | 777 | WP_271272106.1 | SDR family oxidoreductase | - |
PCI15_RS22520 | 4956215..4957171 | - | 957 | WP_271272107.1 | GlxA family transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10585.33 Da Isoelectric Point: 9.7708
>T40242 WP_271272102.1 NZ_AP025281:c4952196-4951924 [Aliamphritea hakodatensis]
MLRLEYSTQFKKDFRKIAKLPIPDVVEVGHVIKELQLGRRLPEKYVDHALSGNWQHYRDCHIKPDLVLIYKTDEGSLKLA
RIGSHSELFR
MLRLEYSTQFKKDFRKIAKLPIPDVVEVGHVIKELQLGRRLPEKYVDHALSGNWQHYRDCHIKPDLVLIYKTDEGSLKLA
RIGSHSELFR
Download Length: 273 bp
>T40242 NZ_AP025281:c4952196-4951924 [Aliamphritea hakodatensis]
ATGCTTAGACTTGAGTATTCCACTCAGTTTAAAAAAGATTTCAGGAAAATCGCGAAGCTTCCGATTCCGGATGTTGTAGA
AGTCGGGCATGTTATCAAAGAGTTACAGTTGGGCAGAAGGTTACCTGAGAAGTACGTTGATCATGCTTTATCGGGTAACT
GGCAACATTATCGTGACTGCCATATTAAGCCGGATCTGGTTTTGATTTATAAAACCGATGAAGGCTCCCTCAAGCTGGCC
CGAATAGGCTCGCATAGCGAGTTATTCCGATAG
ATGCTTAGACTTGAGTATTCCACTCAGTTTAAAAAAGATTTCAGGAAAATCGCGAAGCTTCCGATTCCGGATGTTGTAGA
AGTCGGGCATGTTATCAAAGAGTTACAGTTGGGCAGAAGGTTACCTGAGAAGTACGTTGATCATGCTTTATCGGGTAACT
GGCAACATTATCGTGACTGCCATATTAAGCCGGATCTGGTTTTGATTTATAAAACCGATGAAGGCTCCCTCAAGCTGGCC
CGAATAGGCTCGCATAGCGAGTTATTCCGATAG
Antitoxin
Download Length: 93 a.a. Molecular weight: 9950.34 Da Isoelectric Point: 4.3322
>AT40242 WP_271272103.1 NZ_AP025281:c4952467-4952189 [Aliamphritea hakodatensis]
MKTEMLSARIDQDTKLAFTSVCEEMGLSPSQAIKLFAKAVINYGGIPFELKVKRPNSLTADAIAELESGQGNTVDNVEEL
FDDLKAGKLTDA
MKTEMLSARIDQDTKLAFTSVCEEMGLSPSQAIKLFAKAVINYGGIPFELKVKRPNSLTADAIAELESGQGNTVDNVEEL
FDDLKAGKLTDA
Download Length: 279 bp
>AT40242 NZ_AP025281:c4952467-4952189 [Aliamphritea hakodatensis]
ATGAAAACAGAAATGCTGAGCGCCCGGATTGATCAGGATACTAAACTGGCGTTCACCAGTGTCTGCGAGGAGATGGGATT
GAGCCCCTCTCAGGCGATTAAGCTTTTTGCCAAGGCGGTAATTAATTATGGCGGGATACCGTTTGAGCTAAAGGTGAAGC
GTCCTAATTCTCTGACTGCTGATGCGATTGCAGAGCTGGAGTCCGGTCAGGGGAATACAGTTGATAATGTAGAAGAGCTG
TTTGATGACCTGAAGGCAGGTAAGCTTACAGATGCTTAG
ATGAAAACAGAAATGCTGAGCGCCCGGATTGATCAGGATACTAAACTGGCGTTCACCAGTGTCTGCGAGGAGATGGGATT
GAGCCCCTCTCAGGCGATTAAGCTTTTTGCCAAGGCGGTAATTAATTATGGCGGGATACCGTTTGAGCTAAAGGTGAAGC
GTCCTAATTCTCTGACTGCTGATGCGATTGCAGAGCTGGAGTCCGGTCAGGGGAATACAGTTGATAATGTAGAAGAGCTG
TTTGATGACCTGAAGGCAGGTAAGCTTACAGATGCTTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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