Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 815446..817196 Replicon chromosome
Accession NZ_AP025257
Organism Paraburkholderia terrae strain KU-15

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PTKU15_RS20505 Protein ID WP_229515248.1
Coordinates 816303..817196 (-) Length 298 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PTKU15_RS20500 Protein ID WP_229515249.1
Coordinates 815446..816306 (-) Length 287 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PTKU15_RS20480 (PTKU15_40340) 810643..812139 - 1497 WP_229515252.1 aldehyde dehydrogenase -
PTKU15_RS20485 (PTKU15_40350) 812166..812996 - 831 WP_229515251.1 aspartate dehydrogenase -
PTKU15_RS20490 (PTKU15_40360) 812989..814647 - 1659 WP_042304481.1 thiamine pyrophosphate-binding protein -
PTKU15_RS20495 (PTKU15_40370) 814640..815446 - 807 WP_229515250.1 SDR family oxidoreductase -
PTKU15_RS20500 (PTKU15_40380) 815446..816306 - 861 WP_229515249.1 IclR family transcriptional regulator Antitoxin
PTKU15_RS20505 (PTKU15_40390) 816303..817196 - 894 WP_229515248.1 alpha/beta fold hydrolase Toxin
PTKU15_RS20510 (PTKU15_40400) 817228..817767 - 540 WP_035999007.1 cupin domain-containing protein -
PTKU15_RS20515 (PTKU15_40410) 817803..818561 - 759 WP_248556579.1 SDR family oxidoreductase -
PTKU15_RS20520 (PTKU15_40420) 818554..819642 - 1089 WP_229515246.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
PTKU15_RS20525 (PTKU15_40430) 819685..819996 - 312 WP_042304475.1 hypothetical protein -
PTKU15_RS20530 (PTKU15_40440) 819998..820315 - 318 WP_091781007.1 non-heme iron oxygenase ferredoxin subunit -
PTKU15_RS20535 (PTKU15_40450) 820757..821830 + 1074 WP_229515245.1 porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(50-276)

Antitoxin

Transcription regulator IclR, C-terminal

(144-267)


Sequences

Toxin        


Download         Length: 298 a.a.        Molecular weight: 31204.01 Da        Isoelectric Point: 6.2242

>T40197 WP_229515248.1 NZ_AP025257:c817196-816303 [Paraburkholderia terrae]
MSAALPVTVDRNATLETRLSHFPAQRISIAPQRAMGYREAGAGHADALPLVLLHGIGSGAASWVQQFESLGTTRRVFAWD
APGYGESTPVASASPEANEYASALNAWIDALDIERCVLVGHSLGAIIAGSFAASHAERVAGLLLISPAAGYGAASEEVRA
SKRDSRLAMLAELGPQGLADQRSANMLSPHADDASRDWVRWNMSRIVPHGYAQATHLLANADLASDVAKINGSIAVAVGA
EDSITPPSSCERIAQAARTRLQIIPRAGHAGYIEAGNEYTALIDAFCRASDGQWSKA

Download         Length: 894 bp

>T40197 NZ_AP025257:c817196-816303 [Paraburkholderia terrae]
ATGTCCGCAGCCTTGCCCGTTACTGTCGATCGAAACGCCACGCTGGAAACGCGCCTCTCGCACTTCCCGGCACAGCGGAT
CTCGATTGCGCCGCAACGCGCGATGGGTTATCGCGAGGCGGGTGCCGGCCATGCCGATGCGTTGCCGCTCGTGCTGTTGC
ACGGCATTGGATCGGGCGCGGCTTCGTGGGTGCAACAGTTCGAATCGCTCGGCACGACGCGCCGTGTGTTCGCGTGGGAC
GCGCCGGGCTACGGCGAATCGACGCCAGTCGCGTCGGCGTCGCCTGAAGCAAATGAATATGCGAGCGCGCTCAACGCATG
GATCGACGCGCTCGACATAGAACGTTGCGTGCTGGTCGGTCATTCGCTCGGCGCGATCATCGCGGGCTCGTTCGCAGCGT
CGCATGCGGAACGTGTTGCCGGTCTGCTGCTGATTTCGCCCGCAGCGGGTTACGGCGCGGCATCCGAAGAAGTACGCGCA
TCGAAGCGCGACAGCCGCCTCGCGATGCTCGCCGAACTCGGCCCGCAAGGACTCGCGGACCAACGTAGCGCCAACATGTT
GTCGCCGCACGCCGACGACGCATCGCGCGACTGGGTGCGCTGGAACATGTCGCGCATCGTGCCGCACGGTTACGCGCAGG
CGACGCATCTGCTCGCCAACGCGGACCTCGCCAGCGATGTCGCGAAGATCAACGGCAGTATCGCCGTCGCGGTCGGCGCG
GAAGACTCGATCACGCCGCCGTCGTCATGCGAGCGGATCGCACAGGCGGCGCGTACGCGTTTGCAGATCATCCCGCGCGC
GGGTCACGCGGGCTATATCGAAGCGGGCAATGAATACACCGCGCTCATCGACGCATTCTGCCGCGCGAGCGACGGCCAAT
GGAGCAAAGCATGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31450.87 Da        Isoelectric Point: 6.5092

>AT40197 WP_229515249.1 NZ_AP025257:c816306-815446 [Paraburkholderia terrae]
MTPELTGTAPEAEDDRNDANYRVPGLERGLRILTEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADRDRN
YRLGVAVLRLGFEYLSSLELTDLGLPLIEGLRDATGLTTHIVIRDGRDVVFVAKAQSHAPVFSSVKVNVGTRLPAHATTH
GHVLMGDLSLDELRALYPEKALERFTKHTPATVDELYERVKDDAVRGFAISESSFENGISVISAPVRNDTGRIAAVITTT
IPRPQIDAALLDGGLIDKVRSAAEQLSLRLNYRPSAESRYMKALGL

Download         Length: 861 bp

>AT40197 NZ_AP025257:c816306-815446 [Paraburkholderia terrae]
ATGACCCCCGAATTGACGGGCACTGCGCCTGAAGCAGAAGACGACCGCAACGACGCGAACTACCGCGTGCCCGGTCTCGA
ACGTGGCTTGCGCATTCTCACGGAGTTTTCGCCGCGCGAGCCGGTGCTCGGCGCGCCCGAGTTGTCGAAGCGCCTCGGCA
TTCCGCGCACGACGGTTTTCCGTCTGCTGCAGACGCTCGAATCGCTCGGCTTTCTGGAGCGCGCGGATCGGGACCGCAAC
TATCGCCTGGGCGTCGCGGTACTGCGCCTCGGCTTCGAATATCTCAGTTCGCTCGAACTCACCGATCTCGGCTTGCCGTT
GATCGAAGGCTTGCGCGACGCAACGGGGCTGACCACGCACATCGTGATCCGCGACGGCCGCGACGTGGTGTTCGTCGCGA
AGGCACAAAGCCACGCGCCCGTGTTCAGCTCGGTGAAGGTGAACGTCGGCACACGGCTGCCCGCGCATGCGACCACGCAT
GGCCATGTACTGATGGGTGATCTCTCGCTCGACGAACTGCGCGCGCTGTATCCGGAGAAGGCGCTCGAACGCTTCACGAA
ACACACGCCCGCCACCGTCGACGAACTGTACGAGCGCGTGAAGGACGACGCGGTGCGCGGCTTCGCGATCAGCGAATCAT
CCTTTGAAAACGGCATTTCCGTGATCAGCGCGCCCGTGCGCAACGACACGGGCCGCATCGCCGCCGTCATCACGACGACG
ATTCCGCGTCCGCAGATCGACGCGGCGCTGCTGGATGGCGGCCTGATCGACAAGGTGCGCAGCGCGGCTGAGCAACTGTC
GCTGCGGCTGAACTATCGGCCGTCGGCGGAAAGCAGGTACATGAAGGCATTGGGGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References