Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 706127..706398 Replicon chromosome
Accession NZ_AP025180
Organism Escherichia coli strain JP538

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 706165..706268 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 706127..706398 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
R5G_RS03640 703284..704723 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
R5G_RS03645 704841..705077 + 237 WP_001295499.1 YebV family protein -
R5G_RS03650 705182..705373 + 192 WP_000457842.1 YebW family protein -
R5G_RS03655 705374..706030 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 706127..706398 + 272 - - Antitoxin
- 706165..706268 - 104 - - Toxin
R5G_RS03660 706426..706767 - 342 WP_000976476.1 YebY family protein -
R5G_RS03665 706780..707652 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
R5G_RS03670 707656..708030 - 375 WP_000168747.1 CopC domain-containing protein YobA -
R5G_RS03675 708169..708399 + 231 WP_000916763.1 DNA polymerase III subunit theta -
R5G_RS03680 708501..709157 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
R5G_RS03685 709181..709843 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 690287..775383 85096


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T40033 NZ_AP025180:c706268-706165 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT40033 NZ_AP025180:706127-706398 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References