Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1607764..1608324 Replicon chromosome
Accession NZ_AP024883
Organism Vibrio mangrovi strain CECT 7927

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OCU74_RS07245 Protein ID WP_087479088.1
Coordinates 1607764..1608063 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OCU74_RS07250 Protein ID WP_087479089.1
Coordinates 1608082..1608324 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OCU74_RS07230 1603215..1605854 - 2640 WP_087479086.1 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme -
OCU74_RS07235 1606651..1606989 + 339 WP_087479087.1 aldehyde-activating protein -
OCU74_RS07240 1607320..1607673 + 354 WP_234993510.1 GFA family protein -
OCU74_RS07245 1607764..1608063 - 300 WP_087479088.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OCU74_RS07250 1608082..1608324 - 243 WP_087479089.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OCU74_RS07255 1608665..1609543 + 879 WP_087479090.1 HEPN domain-containing protein -
OCU74_RS07260 1609962..1610339 + 378 WP_087479091.1 polymorphic toxin type 44 domain-containing protein -
OCU74_RS07265 1610317..1610706 + 390 WP_087479092.1 hypothetical protein -
OCU74_RS07270 1611491..1612066 + 576 WP_087479093.1 GIY-YIG nuclease family protein -
OCU74_RS07275 1612118..1612207 + 90 WP_087480054.1 DUF3265 domain-containing protein -
OCU74_RS07280 1612240..1612971 + 732 WP_087479094.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11610.28 Da        Isoelectric Point: 9.5280

>T39790 WP_087479088.1 NZ_AP024883:c1608063-1607764 [Vibrio mangrovi]
MQNKPYKLSYLAQEHLLKIKNYTVENFSEVQWRHYKTILLSGFQTLANNPGLGKKCDEIYRSGFYFHVGKHTTYYTQEDG
FILIVAVLGQSQLPQNHLR

Download         Length: 300 bp

>T39790 NZ_AP024883:c1608063-1607764 [Vibrio mangrovi]
ATGCAAAATAAACCATATAAATTAAGCTATCTCGCACAAGAGCACTTGCTTAAAATCAAAAATTACACGGTTGAAAACTT
TTCAGAAGTACAATGGCGTCACTATAAAACTATTTTACTTTCAGGATTTCAGACTTTAGCCAACAATCCGGGATTAGGAA
AAAAATGTGATGAGATATATCGCAGTGGTTTCTATTTCCATGTGGGCAAACACACCACATATTATACCCAAGAGGATGGT
TTCATCCTGATCGTCGCGGTCTTAGGGCAATCTCAACTGCCACAAAACCACCTTAGATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9030.29 Da        Isoelectric Point: 5.6630

>AT39790 WP_087479089.1 NZ_AP024883:c1608324-1608082 [Vibrio mangrovi]
MRTLTANDAKRNFGELLMNAQREPVKISKNNKDVVVVMSIHDFEALEAMKADYLKHCFESAQKDLTNGTVIDGENFLNSL

Download         Length: 243 bp

>AT39790 NZ_AP024883:c1608324-1608082 [Vibrio mangrovi]
ATGCGCACACTCACAGCAAATGATGCAAAACGAAATTTTGGAGAACTTCTGATGAACGCTCAGCGTGAACCGGTAAAAAT
CAGTAAAAACAATAAAGATGTCGTTGTTGTGATGTCAATTCACGACTTTGAAGCACTTGAAGCGATGAAAGCTGACTACC
TCAAGCATTGCTTTGAATCCGCCCAAAAAGATTTGACCAATGGAACCGTTATTGATGGTGAAAATTTCCTGAACTCGCTT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References