Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 848470..849058 Replicon chromosome
Accession NZ_AP024470
Organism Asaccharobacter celatus DSM 18785

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag ADLECEL_RS03405 Protein ID WP_117285228.1
Coordinates 848470..848778 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag ADLECEL_RS03410 Protein ID WP_117285229.1
Coordinates 848771..849058 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ADLECEL_RS03385 844507..845238 - 732 WP_117285199.1 hypothetical protein -
ADLECEL_RS03390 845601..846635 - 1035 WP_117285200.1 Abi family protein -
ADLECEL_RS03395 847254..847982 + 729 WP_204019678.1 hypothetical protein -
ADLECEL_RS03400 847979..848350 - 372 WP_204019681.1 SEC-C domain-containing protein -
ADLECEL_RS03405 848470..848778 + 309 WP_117285228.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ADLECEL_RS03410 848771..849058 + 288 WP_117285229.1 putative addiction module antidote protein Antitoxin
ADLECEL_RS03415 849238..850065 + 828 WP_117285230.1 ABC transporter permease -
ADLECEL_RS03420 850040..850804 + 765 WP_117285231.1 ABC transporter ATP-binding protein -
ADLECEL_RS03425 850795..851964 - 1170 WP_117285232.1 CDP-glycerol glycerophosphotransferase family protein -
ADLECEL_RS03430 852217..852507 + 291 WP_147319523.1 hypothetical protein -
ADLECEL_RS03435 852544..853221 + 678 WP_147319524.1 DUF4065 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(6-91)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11630.42 Da        Isoelectric Point: 10.4480

>T38468 WP_117285228.1 NZ_AP024470:848470-848778 [Asaccharobacter celatus DSM 18785]
VRIVKSPRYEKWASSLRDRNVIARINARILQIKHYGALTGDWKAVGDGVFELRFHFGAGYRVYIALEGAALLLLLAGGTK
SSQTKDIKLAKEIYESWRRDHE

Download         Length: 309 bp

>T38468 NZ_AP024470:848470-848778 [Asaccharobacter celatus DSM 18785]
GTGAGGATTGTCAAATCTCCGCGTTATGAGAAATGGGCGTCTTCTCTCAGGGATCGCAATGTGATCGCGCGTATCAATGC
GCGGATCCTTCAGATCAAGCACTATGGGGCATTGACGGGGGATTGGAAAGCGGTAGGCGATGGAGTATTCGAGTTGAGAT
TTCATTTCGGAGCTGGATATCGCGTCTATATCGCCCTTGAAGGCGCAGCCCTCCTCCTGCTGCTCGCTGGAGGCACGAAG
TCGTCTCAAACGAAGGACATTAAACTCGCCAAGGAGATCTACGAGTCATGGAGGCGTGACCATGAATAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10164.51 Da        Isoelectric Point: 4.2412

>AT38468 WP_117285229.1 NZ_AP024470:848771-849058 [Asaccharobacter celatus DSM 18785]
MNSEWTEWDPSLDVNSSEDVAAFLNAVLELGDPGILPDALGVIARSRGMKAIAEETGLGRESLYKSLSKSGNPRFSTVVN
VLDCLGFRLQVVPAA

Download         Length: 288 bp

>AT38468 NZ_AP024470:848771-849058 [Asaccharobacter celatus DSM 18785]
ATGAATAGCGAATGGACAGAATGGGACCCATCGTTGGATGTCAATTCCAGCGAGGACGTTGCTGCATTTCTCAATGCCGT
CCTAGAGCTGGGGGATCCAGGGATTCTGCCAGATGCGCTCGGCGTTATCGCCCGATCGCGCGGTATGAAGGCTATCGCCG
AGGAAACGGGCCTCGGGCGCGAGAGCCTCTATAAATCGCTGAGTAAATCGGGCAATCCGCGCTTCAGCACTGTTGTTAAT
GTGCTTGATTGCCTTGGATTCAGGCTTCAGGTCGTGCCTGCTGCTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References