Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1380140..1380623 Replicon chromosome
Accession NZ_AP024276
Organism Streptococcus parasuis strain SUT-286

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L6410_RS06910 Protein ID WP_172016284.1
Coordinates 1380140..1380400 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L6410_RS06915 Protein ID WP_024404858.1
Coordinates 1380402..1380623 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L6410_RS06885 (SUT286_13280) 1375524..1376753 - 1230 WP_024391930.1 tetratricopeptide repeat protein -
L6410_RS06890 (SUT286_13290) 1376743..1377909 - 1167 WP_024397410.1 AI-2E family transporter -
L6410_RS06895 (SUT286_13300) 1378044..1379045 + 1002 WP_237395186.1 lactonase family protein -
L6410_RS06900 (SUT286_13310) 1379112..1379297 + 186 WP_237395187.1 hypothetical protein -
L6410_RS06905 (SUT286_13320) 1379326..1379973 - 648 WP_237395188.1 HAD family hydrolase -
L6410_RS06910 (SUT286_13330) 1380140..1380400 - 261 WP_172016284.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L6410_RS06915 (SUT286_13340) 1380402..1380623 - 222 WP_024404858.1 DUF6290 family protein Antitoxin
L6410_RS06920 (SUT286_13350) 1381143..1382450 - 1308 WP_024391935.1 phosphopyruvate hydratase -
L6410_RS06925 (SUT286_13360) 1382600..1383064 + 465 WP_237395189.1 DUF1694 domain-containing protein -
L6410_RS06930 (SUT286_13370) 1383097..1384848 - 1752 WP_237395190.1 IS1634 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10340.91 Da        Isoelectric Point: 9.9167

>T38284 WP_172016284.1 NZ_AP024276:c1380400-1380140 [Streptococcus parasuis]
MYRLEYSKKAQKQIKKLDRQIQRLLFAWIDKHLEGTENPRANGKGLTGNHAHEWRYRIGDYRLICDIQDDKLVILALEFG
HRKDIY

Download         Length: 261 bp

>T38284 NZ_AP024276:c1380400-1380140 [Streptococcus parasuis]
ATGTATCGTTTAGAGTATTCTAAAAAGGCTCAAAAGCAAATTAAGAAATTAGATAGGCAAATTCAGAGGTTGCTATTTGC
TTGGATTGATAAGCACTTAGAAGGGACTGAAAATCCACGCGCCAATGGTAAAGGTTTGACAGGTAATCATGCTCACGAGT
GGCGTTATCGTATCGGAGATTACCGACTGATTTGCGATATTCAAGATGATAAGTTGGTTATTTTAGCACTTGAGTTTGGA
CATCGTAAAGATATCTATTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8565.57 Da        Isoelectric Point: 4.6104

>AT38284 WP_024404858.1 NZ_AP024276:c1380623-1380402 [Streptococcus parasuis]
MSTVTIRLNQEEEVFFKSYAQLTGQSLSSLFKKALERDIEDEYDLKIYHQAYDEYKANPETISHADFKKELGL

Download         Length: 222 bp

>AT38284 NZ_AP024276:c1380623-1380402 [Streptococcus parasuis]
ATGAGTACAGTAACTATCAGATTAAATCAAGAAGAAGAGGTATTCTTTAAAAGCTATGCACAATTAACAGGTCAAAGTCT
TTCTAGCCTTTTTAAGAAAGCTTTGGAGCGTGATATTGAAGATGAGTATGATTTAAAAATCTATCATCAAGCTTATGATG
AGTACAAAGCAAATCCAGAAACAATTAGTCATGCTGATTTTAAGAAAGAGCTAGGATTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References