Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PHD(antitoxin)
Location 7636829..7637523 Replicon chromosome
Accession NZ_AP022870
Organism Phytohabitans flavus strain NBRC 107702

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag Pflav_RS33730 Protein ID WP_173040803.1
Coordinates 7636829..7637230 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag Pflav_RS33735 Protein ID WP_173040804.1
Coordinates 7637227..7637523 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Pflav_RS33700 7633181..7633708 + 528 WP_173040798.1 hypothetical protein -
Pflav_RS33705 7633831..7634532 + 702 WP_173040799.1 glycosyltransferase family 2 protein -
Pflav_RS33710 7634483..7635382 - 900 WP_173040800.1 transketolase -
Pflav_RS33715 7635388..7636065 - 678 WP_173040801.1 transketolase -
Pflav_RS33720 7636110..7636559 + 450 WP_173040802.1 redox-sensitive transcriptional activator SoxR -
Pflav_RS33730 7636829..7637230 - 402 WP_173040803.1 type II toxin-antitoxin system VapC family toxin Toxin
Pflav_RS33735 7637227..7637523 - 297 WP_173040804.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
Pflav_RS33740 7637622..7638206 + 585 WP_173040805.1 hypothetical protein -
Pflav_RS33745 7638284..7639072 + 789 Protein_6756 ImmA/IrrE family metallo-endopeptidase -
Pflav_RS33750 7639450..7640337 + 888 WP_173040806.1 NAD-dependent epimerase/dehydratase family protein -
Pflav_RS33755 7640386..7640814 + 429 WP_197939026.1 MarR family transcriptional regulator -
Pflav_RS33760 7640819..7641352 + 534 WP_173040808.1 YbhB/YbcL family Raf kinase inhibitor-like protein -
Pflav_RS33765 7641342..7642067 - 726 WP_173042786.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14249.20 Da        Isoelectric Point: 4.5055

>T36620 WP_173040803.1 NZ_AP022870:c7637230-7636829 [Phytohabitans flavus]
VSLYYIDTSAALKLLAQESHSRAFAAFYDESTGASWVSSTLLRIQVIRAVSRAMPAALPDARALLLAFSYVSIDDEVVDA
AMNEPDRMLRSLDAIHLATARVLGPDLDGLATYDDRLAAAAKDAGIPVIDPRG

Download         Length: 402 bp

>T36620 NZ_AP022870:c7637230-7636829 [Phytohabitans flavus]
GTGAGCCTTTACTACATCGACACCTCCGCCGCGCTTAAGTTGCTGGCGCAGGAGAGCCATTCCCGCGCGTTCGCCGCGTT
CTACGACGAAAGCACGGGCGCATCGTGGGTCAGCTCGACATTGCTGCGGATCCAGGTGATCCGCGCAGTCAGCCGTGCCA
TGCCAGCGGCACTGCCGGATGCGAGGGCACTCCTGCTGGCCTTCAGCTACGTGAGCATCGACGATGAGGTCGTGGACGCG
GCGATGAACGAGCCGGACCGGATGCTGCGGTCGCTGGACGCGATTCACCTGGCCACCGCACGGGTGCTCGGGCCGGATCT
GGACGGCCTAGCCACGTATGACGACCGGCTGGCAGCTGCGGCAAAGGACGCCGGAATCCCGGTGATCGACCCGCGAGGTT
GA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10951.46 Da        Isoelectric Point: 8.8078

>AT36620 WP_173040804.1 NZ_AP022870:c7637523-7637227 [Phytohabitans flavus]
MTTLGEHSVGLRELRHNTSEVLARVRHGETIDVTEYGKLVARIVPVGEREPTPVLDRLVEAGRARLAVRPGFRPRMRAGD
GTDRLGDALAALRDEERW

Download         Length: 297 bp

>AT36620 NZ_AP022870:c7637523-7637227 [Phytohabitans flavus]
ATGACGACTCTCGGTGAGCACTCAGTCGGCCTGCGGGAGCTACGCCACAACACCAGTGAGGTGCTGGCGCGCGTGCGGCA
TGGGGAGACGATCGACGTGACGGAGTACGGCAAGCTCGTGGCGCGGATCGTGCCGGTGGGCGAGCGCGAGCCGACACCGG
TGTTGGACCGCTTGGTCGAGGCGGGTCGGGCTCGTTTGGCGGTACGGCCCGGATTTCGGCCGCGGATGCGAGCCGGCGAC
GGCACCGACCGCCTCGGCGATGCCCTCGCGGCCCTGCGCGACGAGGAACGCTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References