Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 108241..108707 Replicon plasmid BTHE68_p2
Accession NZ_AP022320
Organism Burkholderia sp. THE68

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BTHE68_RS35890 Protein ID WP_162071061.1
Coordinates 108471..108707 (+) Length 79 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BTHE68_RS35885 Protein ID WP_162071060.1
Coordinates 108241..108420 (+) Length 60 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTHE68_RS35855 103571..104134 - 564 WP_162071055.1 hypothetical protein -
BTHE68_RS35860 105014..105349 - 336 WP_162071056.1 hypothetical protein -
BTHE68_RS35865 105455..106069 - 615 WP_162071176.1 DNA ligase -
BTHE68_RS35870 106102..106293 - 192 WP_162071057.1 hypothetical protein -
BTHE68_RS35875 106622..107284 + 663 WP_162071058.1 hypothetical protein -
BTHE68_RS35880 107305..107544 + 240 WP_162071059.1 hypothetical protein -
BTHE68_RS35885 108241..108420 + 180 WP_162071060.1 antitoxin Antitoxin
BTHE68_RS35890 108471..108707 + 237 WP_162071061.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BTHE68_RS35895 108822..109127 + 306 WP_162071062.1 hypothetical protein -
BTHE68_RS35900 109376..109714 - 339 WP_162071063.1 H-NS histone family protein -
BTHE68_RS35905 109967..110704 - 738 WP_162071064.1 lytic murein transglycosylase -
BTHE68_RS35910 111109..111525 + 417 WP_162071065.1 hypothetical protein -
BTHE68_RS35915 111603..111917 + 315 WP_162071066.1 hypothetical protein -
BTHE68_RS35920 111971..112330 + 360 WP_162071067.1 hypothetical protein -
BTHE68_RS35925 112242..112601 + 360 WP_174258160.1 hypothetical protein -
BTHE68_RS35930 112680..113084 - 405 WP_162071068.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..243982 243982


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-73)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 8786.24 Da        Isoelectric Point: 7.3152

>T35316 WP_162071061.1 NZ_AP022320:108471-108707 [Burkholderia sp. THE68]
MAFIAQRSPIAATKLFDQILDSVVPASEHPYLFREGRVAGTREIVAHPNYIVIYRVIVDAIVVVQVLHAREEYPPLKS

Download         Length: 237 bp

>T35316 NZ_AP022320:108471-108707 [Burkholderia sp. THE68]
ATGGCCTTCATCGCGCAGCGCAGCCCCATTGCTGCCACCAAACTCTTCGATCAGATCCTCGACTCCGTGGTCCCGGCGTC
CGAGCACCCCTATCTTTTTCGTGAAGGCCGCGTGGCCGGCACGCGCGAGATCGTGGCCCATCCGAACTACATCGTCATCT
ATCGCGTCATCGTTGATGCGATCGTCGTCGTGCAGGTATTGCACGCTCGCGAGGAGTACCCGCCTCTGAAGTCGTAG

Antitoxin


Download         Length: 60 a.a.        Molecular weight: 6702.43 Da        Isoelectric Point: 4.7164

>AT35316 WP_162071060.1 NZ_AP022320:108241-108420 [Burkholderia sp. THE68]
MSTSLSPIESEFDTEEQAASHDRWFRAKVQEALDDPRPLVPHDEVVADIRKTIANAKPR

Download         Length: 180 bp

>AT35316 NZ_AP022320:108241-108420 [Burkholderia sp. THE68]
ATGAGCACATCCCTTTCGCCCATCGAGTCGGAATTCGACACCGAGGAACAGGCCGCTTCCCATGACCGCTGGTTTCGCGC
CAAGGTCCAAGAAGCGCTCGATGACCCGCGCCCGCTCGTGCCGCACGATGAAGTCGTGGCCGACATCCGCAAGACCATCG
CTAACGCCAAACCGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References