Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 964434..964705 Replicon chromosome
Accession NZ_AP021896
Organism Escherichia coli strain 2018-02-2CC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 964472..964575 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 964434..964705 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR25_RS04650 961591..963030 + 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HRR25_RS04655 963148..963384 + 237 WP_001338166.1 DUF1480 family protein -
HRR25_RS04660 963489..963680 + 192 WP_001338167.1 YebW family protein -
HRR25_RS04665 963681..964337 - 657 WP_000812732.1 protein-serine/threonine phosphatase -
- 964434..964705 + 272 - - Antitoxin
- 964472..964575 - 104 - - Toxin
HRR25_RS04670 964733..965074 - 342 WP_000976472.1 YebY family protein -
HRR25_RS04675 965087..965959 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
HRR25_RS04680 965963..966337 - 375 WP_000168747.1 CopC domain-containing protein YobA -
HRR25_RS04685 966476..966706 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HRR25_RS04690 966808..967464 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HRR25_RS04695 967488..968150 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 956204..989412 33208


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T33654 NZ_AP021896:c964575-964472 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT33654 NZ_AP021896:964434-964705 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References