33510

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3101489..3102008 Replicon chromosome
Accession NZ_AP021884
Organism Sulfuriferula plumbiphila strain Gro7

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag GZH91_RS15925 Protein ID WP_161984301.1
Coordinates 3101700..3102008 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag GZH91_RS15920 Protein ID WP_147074160.1
Coordinates 3101489..3101716 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZH91_RS15900 3097300..3097875 + 576 WP_147074167.1 Uma2 family endonuclease -
GZH91_RS15905 3097868..3098866 + 999 WP_147074165.1 glycosyltransferase family 4 protein -
GZH91_RS15910 3098969..3099229 + 261 WP_147074163.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
GZH91_RS15915 3099356..3101218 + 1863 WP_147074162.1 polysaccharide biosynthesis protein -
GZH91_RS15920 3101489..3101716 + 228 WP_147074160.1 ribbon-helix-helix protein, CopG family Antitoxin
GZH91_RS15925 3101700..3102008 + 309 WP_161984301.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GZH91_RS15930 3102302..3103777 - 1476 WP_147075110.1 Fic family protein -
GZH91_RS15935 3104133..3104555 - 423 WP_147075109.1 type II toxin-antitoxin system VapC family toxin -
GZH91_RS15940 3104552..3104803 - 252 WP_198415337.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
GZH91_RS15945 3105696..3106601 - 906 WP_147075107.1 glycosyltransferase family 2 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3093928..3113925 19997


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-69)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11253.14 Da        Isoelectric Point: 11.1227

>T33510 WP_161984301.1 NZ_AP021884:3101700-3102008 [Sulfuriferula plumbiphila]
MVWRIELTATAAKRLAKLDKGEAKRITSFLRQRLAVLDDPRTTGKALTGPHLGAYWRYRVGDYRIILETAVGRARWCVWA
CGCAKQRGATKAGARPDVPAGA

Download         Length: 309 bp

>T33510 NZ_AP021884:3101700-3102008 [Sulfuriferula plumbiphila]
TTGGTTTGGCGGATTGAGCTGACGGCCACGGCGGCCAAGCGGCTCGCGAAACTCGACAAGGGCGAAGCCAAACGCATCAC
AAGCTTTCTTCGACAACGCCTCGCTGTGCTCGATGACCCACGCACCACAGGTAAGGCGCTCACAGGCCCGCATCTCGGCG
CATACTGGCGCTACCGCGTCGGCGACTATCGAATCATCCTAGAAACCGCAGTTGGACGCGCCCGATGGTGCGTTTGGGCG
TGTGGCTGCGCGAAGCAACGAGGCGCGACAAAGGCAGGCGCGCGACCGGACGTGCCAGCGGGTGCGTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8629.77 Da        Isoelectric Point: 4.8550

>AT33510 WP_147074160.1 NZ_AP021884:3101489-3101716 [Sulfuriferula plumbiphila]
MATSIRLDPEIEQRLDHLAAQTGRTKAYYLRELIANGLKDLEDHYLAAATMERIRKGEERVFTLEEVERNLGLAD

Download         Length: 228 bp

>AT33510 NZ_AP021884:3101489-3101716 [Sulfuriferula plumbiphila]
ATGGCAACTTCAATCCGGCTCGATCCGGAAATCGAGCAGCGGCTAGACCACCTGGCCGCACAGACAGGCCGTACCAAGGC
ATATTACCTGCGCGAGCTAATCGCGAATGGCCTGAAAGACCTGGAAGACCACTACCTGGCTGCCGCGACGATGGAGCGCA
TCCGCAAGGGCGAAGAACGCGTTTTCACGCTGGAGGAAGTGGAGCGCAATCTTGGTTTGGCGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References