Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2590197..2590381 Replicon chromosome
Accession NZ_AP019751
Organism Staphylococcus aureus strain JRA307

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag FPG46_RS13370 Protein ID WP_000482647.1
Coordinates 2590274..2590381 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2590197..2590257 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPG46_RS13355 2585671..2585838 - 168 WP_001790576.1 hypothetical protein -
FPG46_RS13360 2586069..2587802 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
FPG46_RS13365 2587827..2589590 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
- 2590197..2590257 + 61 - - Antitoxin
FPG46_RS13370 2590274..2590381 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
FPG46_RS13375 2590515..2590901 - 387 WP_000779360.1 flippase GtxA -
FPG46_RS13380 2591159..2592301 + 1143 WP_001176871.1 glycerate kinase -
FPG46_RS13385 2592361..2593020 + 660 WP_000831301.1 membrane protein -
FPG46_RS13390 2593202..2594413 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
FPG46_RS13395 2594536..2595009 - 474 WP_144079014.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T32984 WP_000482647.1 NZ_AP019751:c2590381-2590274 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T32984 NZ_AP019751:c2590381-2590274 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT32984 NZ_AP019751:2590197-2590257 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References