Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1971243..1971514 Replicon chromosome
Accession NZ_AP019675
Organism Escherichia coli strain GSH8M-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1971373..1971476 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1971243..1971514 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GDK32_RS09585 1967798..1968460 - 663 WP_000944258.1 exodeoxyribonuclease X -
GDK32_RS09590 1968484..1969140 - 657 WP_001752600.1 carbon-nitrogen hydrolase family protein -
GDK32_RS09595 1969242..1969472 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GDK32_RS09600 1969611..1969985 + 375 WP_000168747.1 CopC domain-containing protein YobA -
GDK32_RS09605 1969989..1970861 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
GDK32_RS09610 1970874..1971215 + 342 WP_000976472.1 YebY family protein -
- 1971243..1971514 - 272 - - Antitoxin
- 1971373..1971476 + 104 - - Toxin
GDK32_RS09615 1971611..1972267 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
GDK32_RS09620 1972268..1972459 - 192 WP_001338167.1 YebW family protein -
GDK32_RS09625 1972564..1972800 - 237 WP_001338166.1 DUF1480 family protein -
GDK32_RS09630 1972918..1974357 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T32868 NZ_AP019675:1971373-1971476 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT32868 NZ_AP019675:c1971514-1971243 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References