Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2062841..2063112 Replicon chromosome
Accession NZ_AP019189
Organism Escherichia coli strain M217

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2062971..2063074 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2062841..2063112 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7R44_RS10635 2059396..2060058 - 663 WP_000944256.1 exodeoxyribonuclease X -
B7R44_RS10640 2060082..2060738 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
B7R44_RS10645 2060840..2061070 - 231 WP_000916763.1 DNA polymerase III subunit theta -
B7R44_RS10650 2061209..2061583 + 375 WP_000168747.1 CopC domain-containing protein YobA -
B7R44_RS10655 2061587..2062459 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
B7R44_RS10660 2062472..2062813 + 342 WP_000976476.1 YebY family protein -
- 2062841..2063112 - 272 - - Antitoxin
- 2062971..2063074 + 104 - - Toxin
B7R44_RS10665 2063209..2063865 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
B7R44_RS10670 2063866..2064057 - 192 WP_000457842.1 YebW family protein -
B7R44_RS10675 2064162..2064398 - 237 WP_001295499.1 DUF1480 family protein -
B7R44_RS10680 2064516..2065955 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T32535 NZ_AP019189:2062971-2063074 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT32535 NZ_AP019189:c2063112-2062841 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References