Detailed information of TA system TA031447

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-Xre
• Location: 78120..79002
• Replicon: plasmid pANY103a
• Accession: NZ_AP017987
• Organism: Aminobacter sp. SS-2016 strain Y103A

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: Amn_RS27930
• Protein ID: WP_286298873.1
• Coordinates: 78484..79002 (+)
• Length: 173 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A7W3KUD3
• Locus tag: Amn_RS27925
• Protein ID: WP_067967357.1
• Coordinates: 78120..78491 (+)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Amn_RS27910 (Amn_pa00710)	74260..76092	+	1833	WP_286298867.1	ABC transporter ATP-binding protein	-
Amn_RS27915 (Amn_pa00720)	76296..77249	+	954	WP_286298869.1	DUF1403 family protein	-
Amn_RS27920 (Amn_pa00730)	77252..77929	+	678	WP_286298871.1	SMC-Scp complex subunit ScpB	-
Amn_RS27925 (Amn_pa00740)	78120..78491	+	372	WP_067967357.1	DUF2384 domain-containing protein	Antitoxin
Amn_RS27930 (Amn_pa00750)	78484..79002	+	519	WP_286298873.1	RES domain-containing protein	Toxin
Amn_RS27935 (Amn_pa00760)	79382..80491	+	1110	WP_286299084.1	transporter substrate-binding domain-containing protein	-
Amn_RS27940 (Amn_pa00770)	80535..81200	+	666	WP_286298874.1	ANTAR domain-containing protein	-
Amn_RS27945 (Amn_pa00780)	81514..82551	+	1038	WP_286298875.1	alpha/beta fold hydrolase	-
Amn_RS27950 (Amn_pa00790)	82639..83886	+	1248	WP_286298878.1	transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..519431	519431

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (11-164)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (22-63)

Sequences

Toxin

Protein

• Length: 173 a.a.
• Molecular weight: 19161.75 Da
• Isoelectric Point: 5.5677

>T31447 WP_286298873.1 NZ_AP017987:78484-79002 [Aminobacter sp. SS-2016]
MPEAALRQQRTLWRAFVPRWAHMPLSGEGAARFGGRWNPVGSPTLYAACELSTAWAEYNQGFVQHPALIAQLELSDARLA
DLTDAAMLDELGIDAGIHRCEWRSDLDEGRVPETHLFRQRLLTDGFDGVVYPSFMSPGGSCVALWHWNGPGQPILKVIDP
DQRLPKTPASWL

Nucleotide

• Length: 519 bp

>T31447 NZ_AP017987:78484-79002 [Aminobacter sp. SS-2016]
ATGCCTGAAGCCGCCCTGCGTCAGCAGCGAACCTTGTGGCGGGCCTTCGTGCCGCGCTGGGCGCACATGCCGCTTTCGGG
CGAGGGCGCTGCGCGTTTCGGCGGGCGCTGGAACCCGGTAGGATCGCCGACGCTGTATGCGGCCTGTGAGCTGTCGACCG
CCTGGGCTGAATACAACCAGGGTTTTGTCCAGCATCCGGCGTTGATCGCCCAGCTCGAGCTGTCGGACGCGAGGCTGGCC
GACCTGACCGATGCCGCGATGCTGGACGAACTCGGCATCGATGCCGGCATTCACAGATGCGAGTGGCGTTCCGATCTCGA
TGAGGGCAGGGTACCGGAAACCCATCTTTTTCGGCAGCGCCTGCTGACTGACGGCTTCGACGGCGTCGTCTATCCCTCGT
TCATGTCTCCCGGCGGCAGTTGCGTTGCGTTGTGGCACTGGAACGGTCCAGGCCAGCCGATACTCAAGGTCATAGATCCT
GATCAGCGCTTGCCGAAGACACCGGCCTCCTGGCTCTAA

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13028.98 Da
• Isoelectric Point: 10.2736

>AT31447 WP_067967357.1 NZ_AP017987:78120-78491 [Aminobacter sp. SS-2016]
MAAQSLGMSAAHFGEARSQFLSARRVSELLGVTQADLARLVGVARNTLTARSGARKVDQALSPVVRILAMAAEMAGDESR
AAIWFKHQPIPGWAGKTAYDLVGEGKADKVLAYLEAVRSGVYA

Nucleotide

• Length: 372 bp

>AT31447 NZ_AP017987:78120-78491 [Aminobacter sp. SS-2016]
ATGGCAGCTCAGAGTTTGGGAATGTCGGCGGCCCATTTCGGTGAAGCCCGGTCGCAGTTTCTCTCGGCTCGCCGCGTGTC
GGAGCTGCTGGGTGTCACCCAGGCCGACCTGGCCCGGCTCGTTGGCGTTGCCCGCAACACGCTGACGGCGCGCTCCGGGG
CACGCAAGGTCGACCAGGCGCTCAGCCCCGTCGTCCGCATCCTGGCGATGGCCGCCGAAATGGCCGGCGACGAGAGCCGT
GCAGCGATCTGGTTCAAGCATCAGCCGATCCCGGGTTGGGCCGGCAAGACGGCCTATGACCTGGTCGGTGAGGGCAAGGC
GGACAAGGTCCTGGCTTATCTGGAGGCGGTGCGCTCCGGCGTTTATGCCTGA

Structures

Antitoxin

• AlphaFold DB: A0A7W3KUD3