Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 3012233..3013488 Replicon chromosome
Accession NZ_AP014628
Organism Pseudomonas sp. St29

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PST29_RS13725 Protein ID WP_060843388.1
Coordinates 3012916..3013488 (+) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PST29_RS13720 Protein ID WP_060843387.1
Coordinates 3012233..3012790 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PST29_RS13690 3007240..3007521 - 282 WP_060843382.1 type II toxin-antitoxin system ParD family antitoxin -
PST29_RS13695 3007629..3008249 - 621 WP_060843383.1 LysE family translocator -
PST29_RS13700 3008420..3008992 - 573 WP_060843384.1 inclusion body family protein -
PST29_RS32140 3009014..3009166 - 153 WP_159426281.1 hypothetical protein -
PST29_RS13705 3009217..3009846 - 630 WP_060843385.1 alpha/beta hydrolase -
PST29_RS13710 3010079..3011275 + 1197 WP_060843386.1 PrpF protein -
PST29_RS13715 3011702..3012043 - 342 WP_060845117.1 low molecular weight protein tyrosine phosphatase family protein -
PST29_RS13720 3012233..3012790 + 558 WP_060843387.1 helix-turn-helix domain-containing protein Antitoxin
PST29_RS13725 3012916..3013488 + 573 WP_060843388.1 HD domain-containing protein Toxin
PST29_RS13730 3013745..3015925 + 2181 WP_060843389.1 catalase/peroxidase HPI -
PST29_RS13735 3015987..3016673 - 687 WP_060838975.1 hypothetical protein -
PST29_RS13740 3016633..3017253 - 621 WP_060838976.1 hypothetical protein -
PST29_RS13745 3017320..3017748 - 429 WP_060838977.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD/PDEase domain

(34-140)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-47)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21525.09 Da        Isoelectric Point: 4.7436

>T30793 WP_060843388.1 NZ_AP014628:3012916-3013488 [Pseudomonas sp. St29]
MTPELLSGRLDFLREAEKLKDVLRSAHTSSGRQESTAEHSWRLCLMALLFEDQLGDLDLLRVLKLCIVHDLGEAIHGDIP
AVAQAAHPDKSQQERDDLQYLARALDAPARQRLLELWDEYEGAASTEARAVKALDKLEALLQHTQGQNPADFDYGFNLDY
GRRYTDASPLFQALRQQIDADTRRRLDAQD

Download         Length: 573 bp

>T30793 NZ_AP014628:3012916-3013488 [Pseudomonas sp. St29]
ATGACCCCCGAACTCCTCAGCGGCCGTCTCGACTTTCTCCGTGAAGCGGAAAAGCTCAAGGACGTGCTGCGCAGCGCCCA
CACCTCCAGCGGCCGCCAGGAAAGCACCGCCGAGCACAGCTGGCGCCTGTGCCTGATGGCGCTGCTGTTCGAAGACCAAC
TGGGGGACCTGGACCTGCTGCGGGTGCTGAAACTGTGCATCGTCCACGACCTGGGGGAAGCCATTCATGGCGACATCCCG
GCGGTGGCCCAGGCCGCCCACCCGGACAAGAGCCAGCAGGAACGCGACGACCTGCAATACCTCGCCCGGGCCCTGGACGC
CCCGGCCCGCCAGCGCCTGCTGGAGCTGTGGGATGAATACGAAGGCGCCGCCAGCACCGAGGCGCGCGCGGTCAAGGCCC
TGGACAAGCTGGAAGCCCTGCTGCAACACACCCAGGGCCAGAACCCGGCGGATTTCGACTACGGCTTCAACCTCGATTAC
GGCCGCCGCTACACCGACGCCAGCCCGTTGTTCCAGGCCCTGCGCCAGCAGATCGATGCCGACACTCGGCGCCGCCTCGA
CGCCCAGGACTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20416.37 Da        Isoelectric Point: 7.4189

>AT30793 WP_060843387.1 NZ_AP014628:3012233-3012790 [Pseudomonas sp. St29]
MSAALFTSPHLGLALRRWRLLHRVKQQHAAELFGVAQSSISRWENGRQAMEPAERARLEHLLAANLSAAADQALARLVND
SPRAVHLVCDLTHRLLACSPTRAAQFGVPLSELLGQSLWGFCTEEIVRKEAALDDLGWREVLAPPSLEFFSGHNDSAIVP
IAPSQCRWTRLNLSDGNAVRLVETL

Download         Length: 558 bp

>AT30793 NZ_AP014628:3012233-3012790 [Pseudomonas sp. St29]
ATGTCCGCAGCCCTGTTCACCTCACCCCATCTGGGCCTGGCCCTCAGGCGCTGGCGCCTGTTGCACCGGGTCAAGCAGCA
GCACGCCGCCGAGCTGTTCGGCGTGGCGCAGTCGAGCATTTCCCGCTGGGAAAACGGCCGGCAAGCCATGGAGCCGGCGG
AGCGTGCGCGCCTGGAGCACCTGCTGGCGGCCAACCTCAGCGCCGCTGCCGATCAGGCTCTGGCGCGGCTGGTGAATGAC
AGCCCGCGCGCCGTGCACCTGGTGTGCGACCTGACCCACCGCCTGCTGGCCTGTTCGCCGACCCGCGCCGCACAATTCGG
CGTGCCCTTGAGTGAGCTGCTGGGCCAATCGCTGTGGGGCTTTTGCACCGAGGAAATCGTGCGCAAGGAAGCCGCCCTGG
ATGACCTGGGCTGGCGCGAAGTGCTGGCGCCGCCGTCCCTGGAGTTCTTCAGCGGCCACAACGATTCGGCCATCGTGCCC
ATCGCCCCCAGCCAGTGCCGCTGGACCCGCCTCAACCTGTCCGACGGCAACGCCGTGCGGCTGGTGGAAACCCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References