Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2652971..2653155 Replicon chromosome
Accession NC_022604
Organism Staphylococcus aureus subsp. aureus Z172

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag SAZ172_RS13830 Protein ID WP_000482650.1
Coordinates 2653048..2653155 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2652971..2653031 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAZ172_RS13805 2648501..2648668 - 168 WP_001790576.1 hypothetical protein -
SAZ172_RS13815 2648899..2650632 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
SAZ172_RS13820 2650657..2652420 - 1764 WP_023180203.1 ABC transporter ATP-binding protein/permease -
- 2652971..2653031 + 61 - - Antitoxin
SAZ172_RS13830 2653048..2653155 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
SAZ172_RS13835 2653288..2653674 - 387 WP_000779358.1 flippase GtxA -
SAZ172_RS13840 2653942..2655084 + 1143 WP_001176863.1 glycerate kinase -
SAZ172_RS13845 2655144..2655803 + 660 WP_000831298.1 membrane protein -
SAZ172_RS13850 2655985..2657196 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
SAZ172_RS13855 2657319..2657792 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T30229 WP_000482650.1 NC_022604:c2653155-2653048 [Staphylococcus aureus subsp. aureus Z172]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T30229 NC_022604:c2653155-2653048 [Staphylococcus aureus subsp. aureus Z172]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT30229 NC_022604:2652971-2653031 [Staphylococcus aureus subsp. aureus Z172]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References