Detailed information of TA system TA295824

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-rdlD/Ldr(toxin)
• Location: 183057..183279
• Replicon: chromosome
• Accession: NZ_OW967795
• Organism: Escherichia coli isolate 538

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: A0A3K0NFU8
• Locus tag: LQ148_RS00860
• Protein ID: WP_000170748.1
• Coordinates: 183172..183279 (+)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	rdlD
Locus tag	-
Coordinates	183057..183115 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LQ148_RS00840	178928..179911	+	984	WP_001196477.1	dipeptide ABC transporter ATP-binding protein	-
LQ148_RS00845	179908..180912	+	1005	WP_000103571.1	dipeptide ABC transporter ATP-binding subunit DppF	-
LQ148_RS00850	180942..182213	-	1272	WP_001296513.1	aromatic amino acid transport family protein	-
LQ148_RS00855	182689..182796	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
-	183057..183115	-	59	-	-	Antitoxin
LQ148_RS00860	183172..183279	+	108	WP_000170748.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
LQ148_RS00865	183655..183762	+	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	-
LQ148_RS00870	183848..185527	-	1680	WP_022296260.1	cellulose biosynthesis protein BcsG	-
LQ148_RS00875	185524..185715	-	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
LQ148_RS00880	185712..187283	-	1572	WP_001204941.1	cellulose biosynthesis c-di-GMP-binding protein BcsE	-
LQ148_RS00885	187556..187744	+	189	WP_001063314.1	cellulose biosynthesis protein BcsR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3913.76 Da
• Isoelectric Point: 9.0157

>T295824 WP_000170748.1 NZ_OW967795:183172-183279 [Escherichia coli]
MTLAELGMAFWHDLAVPVITGILASMIVSWLNKRK

Nucleotide

• Length: 108 bp

Antitoxin

Nucleotide

• Length: 59 bp

>AT295824 NZ_OW967795:c183115-183057 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Structures

Toxin

• AlphaFold DB: A0A3K0NFU8

Antitoxin