Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 636480..636955 Replicon chromosome
Accession NC_021294
Organism Burkholderia sp. RPE64

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BRPE64_RS32380 Protein ID WP_016354722.1
Coordinates 636674..636955 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BRPE64_RS17030 Protein ID WP_044042354.1
Coordinates 636480..636677 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRPE64_RS17010 632320..634059 + 1740 WP_016354717.1 FAD-dependent oxidoreductase -
BRPE64_RS17015 634056..634667 + 612 WP_016354718.1 NIPSNAP family protein -
BRPE64_RS17020 634682..635506 + 825 WP_016354719.1 sugar phosphate isomerase/epimerase -
BRPE64_RS17025 635575..636381 + 807 WP_016354720.1 IclR family transcriptional regulator -
BRPE64_RS17030 636480..636677 + 198 WP_044042354.1 hypothetical protein Antitoxin
BRPE64_RS32380 636674..636955 + 282 WP_016354722.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BRPE64_RS17040 637179..637757 + 579 WP_044042356.1 hypothetical protein -
BRPE64_RS17045 637774..638418 - 645 WP_044042357.1 XRE family transcriptional regulator -
BRPE64_RS17050 638728..640227 + 1500 WP_044042358.1 aldehyde dehydrogenase family protein -
BRPE64_RS17055 640278..641450 + 1173 WP_044042359.1 FAD-binding oxidoreductase -
BRPE64_RS17060 641737..641934 + 198 WP_016354727.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10416.96 Da        Isoelectric Point: 8.8740

>T29520 WP_016354722.1 NC_021294:636674-636955 [Caballeronia insecticola]
MTLHVVWTQNARLDLLEIIRYIAERSPGAARAVKSALDAAPQAAATAPYLYRNGRVPGTREIVVHPNYVIVYSVTDRIEV
LNVLHSRQCYPSE

Download         Length: 282 bp

>T29520 NC_021294:636674-636955 [Caballeronia insecticola]
TTGACGCTGCATGTTGTCTGGACCCAAAACGCACGCCTCGATCTTCTGGAAATCATCCGCTACATCGCAGAACGCAGTCC
CGGTGCCGCCCGCGCAGTCAAAAGCGCGCTCGATGCAGCGCCGCAGGCTGCCGCCACGGCTCCTTACCTGTATCGCAATG
GTCGCGTTCCGGGTACCCGAGAGATCGTCGTGCACCCGAATTACGTCATCGTCTACTCGGTGACGGACCGCATCGAAGTC
CTGAACGTGCTCCATTCACGGCAGTGTTACCCGTCTGAATGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7505.44 Da        Isoelectric Point: 5.1373

>AT29520 WP_044042354.1 NC_021294:636480-636677 [Caballeronia insecticola]
MTTPLDPIVSEFATVEEAEAYDKWFREKVRRSMADTRPRIAHDEVMAEAEAIITEAEKRHKSRSA

Download         Length: 198 bp

>AT29520 NC_021294:636480-636677 [Caballeronia insecticola]
ATGACAACCCCGCTCGATCCTATCGTGTCCGAGTTCGCCACTGTTGAAGAAGCGGAAGCCTATGACAAATGGTTTCGCGA
AAAAGTGCGGCGCTCGATGGCCGATACGCGGCCGCGTATTGCGCATGATGAGGTGATGGCCGAGGCAGAAGCAATCATTA
CCGAAGCCGAGAAACGTCACAAGTCGAGGTCCGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References