Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1974554..1974697 Replicon chromosome
Accession NZ_OU943337
Organism Salmonella enterica subsp. enterica serovar Typhi strain MDUST255

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1974593..1974695 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1974554..1974697 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AE465_RS09520 (SAMEA2145578_01932) 1970978..1971676 - 699 WP_000944282.1 exodeoxyribonuclease X -
AE465_RS09525 (SAMEA2145578_01933) 1971700..1972356 - 657 WP_000100250.1 carbon-nitrogen hydrolase family protein -
AE465_RS09530 (SAMEA2145578_01934) 1972464..1972694 - 231 WP_000856224.1 DNA polymerase III subunit theta -
AE465_RS09535 (SAMEA2145578_01935) 1972832..1973206 + 375 WP_001681742.1 CopC domain-containing protein YobA -
AE465_RS09540 (SAMEA2145578_01936) 1973207..1974082 + 876 WP_000979693.1 copper homeostasis membrane protein CopD -
AE465_RS09545 (SAMEA2145578_01937) 1974099..1974452 + 354 WP_000722366.1 YebY family protein -
- 1974554..1974697 - 144 - - Antitoxin
- 1974593..1974695 + 103 - - Toxin
AE465_RS09550 (SAMEA2145578_01938) 1974816..1975124 - 309 Protein_1866 tyrosine-type recombinase/integrase -
AE465_RS09555 1975123..1975484 - 362 Protein_1867 recombinase RecT -
AE465_RS09560 1975485..1975595 + 111 Protein_1868 replication protein -
AE465_RS09565 1975608..1976003 + 396 Protein_1869 DUF977 family protein -
AE465_RS09570 (SAMEA2145578_01940) 1976289..1977419 - 1131 WP_000529513.1 GGDEF domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 1952681..2005884 53203


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T294924 NZ_OU943337:1974593-1974695 [Salmonella enterica subsp. enterica serovar Typhi]
GCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT294924 NZ_OU943337:c1974697-1974554 [Salmonella enterica subsp. enterica serovar Typhi]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCTCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References