Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
Location | 2803753..2804996 | Replicon | chromosome |
Accession | NZ_LT632614 | ||
Organism | Legionella pneumophila strain ST62 isolate ST62 |
Toxin (Protein)
Gene name | HipT | Uniprot ID | - |
Locus tag | BT141_RS12860 | Protein ID | WP_042754550.1 |
Coordinates | 2804058..2804996 (+) | Length | 313 a.a. |
Antitoxin (Protein)
Gene name | HipS | Uniprot ID | - |
Locus tag | BT141_RS12855 | Protein ID | WP_027224429.1 |
Coordinates | 2803753..2804061 (+) | Length | 103 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BT141_RS12830 | 2799426..2799623 | - | 198 | WP_014842401.1 | hypothetical protein | - |
BT141_RS12835 | 2799643..2800869 | - | 1227 | WP_015961555.1 | MFS transporter | - |
BT141_RS12840 | 2801505..2801978 | + | 474 | WP_027224431.1 | hypothetical protein | - |
BT141_RS12845 | 2802168..2803085 | + | 918 | WP_042754552.1 | LysR family transcriptional regulator | - |
BT141_RS12850 | 2803529..2803756 | + | 228 | WP_013101792.1 | helix-turn-helix transcriptional regulator | - |
BT141_RS12855 | 2803753..2804061 | + | 309 | WP_027224429.1 | HipA N-terminal domain-containing protein | Antitoxin |
BT141_RS12860 | 2804058..2804996 | + | 939 | WP_042754550.1 | HipA domain-containing protein | Toxin |
BT141_RS12865 | 2805159..2805869 | - | 711 | WP_027225948.1 | outer membrane beta-barrel protein | - |
BT141_RS12875 | 2806352..2806645 | - | 294 | WP_042754549.1 | SNARE domain-containing protein | - |
BT141_RS12880 | 2806673..2807575 | - | 903 | WP_042754548.1 | hypothetical protein | - |
BT141_RS12885 | 2807738..2809192 | + | 1455 | WP_027225951.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 313 a.a. Molecular weight: 36063.60 Da Isoelectric Point: 8.9515
>T293405 WP_042754550.1 NZ_LT632614:2804058-2804996 [Legionella pneumophila]
MKRCPITYEKISDQENYSQRGLRLLSPQLKNLSPLDLSADEQRQEAIARVGKTSIQGVQKKLSAKLKIKEGCFEIVDQNG
HYILKPQSDIYPELPENEAITMTLAKTIGLEVPVHGLVYSKDNSLTYFIKRFDRIGHNKKLALEDFAQLSGEDRHTKYKS
SMEKVIAIIEQFCTFPKIEFVKLFKLTLFNFLVGNEDMHLKNFSLITRDRKISISPAYDLLNSTIAQKNTKEEIALPLKG
EKNNLTKSDFFNYFAVEKLGLNQNVINGIAQEFHQAIPEWRELISFSFLSQPMQEKYLQLLDQRCKRLNFFD
MKRCPITYEKISDQENYSQRGLRLLSPQLKNLSPLDLSADEQRQEAIARVGKTSIQGVQKKLSAKLKIKEGCFEIVDQNG
HYILKPQSDIYPELPENEAITMTLAKTIGLEVPVHGLVYSKDNSLTYFIKRFDRIGHNKKLALEDFAQLSGEDRHTKYKS
SMEKVIAIIEQFCTFPKIEFVKLFKLTLFNFLVGNEDMHLKNFSLITRDRKISISPAYDLLNSTIAQKNTKEEIALPLKG
EKNNLTKSDFFNYFAVEKLGLNQNVINGIAQEFHQAIPEWRELISFSFLSQPMQEKYLQLLDQRCKRLNFFD
Download Length: 939 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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