Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2445364..2445548 Replicon chromosome
Accession NZ_LT615218
Organism Staphylococcus aureus strain AUS0325

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag BQ3358_RS12510 Protein ID WP_000482647.1
Coordinates 2445441..2445548 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2445364..2445424 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BQ3358_RS12485 2440894..2441061 - 168 WP_001792506.1 hypothetical protein -
BQ3358_RS12495 2441292..2443025 - 1734 WP_000486491.1 ABC transporter ATP-binding protein/permease -
BQ3358_RS12500 2443050..2444813 - 1764 WP_001064816.1 ABC transporter ATP-binding protein/permease -
- 2445364..2445424 + 61 - - Antitoxin
BQ3358_RS12510 2445441..2445548 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
BQ3358_RS12515 2445682..2446068 - 387 WP_000779347.1 flippase GtxA -
BQ3358_RS12520 2446326..2447468 + 1143 WP_001176863.1 glycerate kinase -
BQ3358_RS12525 2447528..2448187 + 660 WP_000831298.1 membrane protein -
BQ3358_RS12530 2448369..2449580 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
BQ3358_RS12535 2449703..2450176 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T293317 WP_000482647.1 NZ_LT615218:c2445548-2445441 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT293317 NZ_LT615218:2445364-2445424 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References