Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2515101..2515285 Replicon chromosome
Accession NZ_LT009690
Organism Staphylococcus aureus strain NZAK3

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag NZAK3_RS12890 Protein ID WP_000482652.1
Coordinates 2515178..2515285 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2515101..2515161 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZAK3_RS12865 2510556..2510723 - 168 Protein_2437 hypothetical protein -
NZAK3_RS12875 2510954..2512687 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
NZAK3_RS12880 2512712..2514475 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
NZAK3_RS12890 2515178..2515285 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
NZAK3_RS12895 2515419..2515805 - 387 WP_000779360.1 flippase GtxA -
NZAK3_RS12900 2516073..2517215 + 1143 WP_001176863.1 glycerate kinase -
NZAK3_RS12905 2517275..2517934 + 660 WP_000831298.1 membrane protein -
NZAK3_RS12910 2518116..2519327 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NZAK3_RS12915 2519450..2519923 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T293111 WP_000482652.1 NZ_LT009690:c2515285-2515178 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT293111 NZ_LT009690:2515101-2515161 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References