Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2110795..2111066 Replicon chromosome
Accession NZ_LS992166
Organism Escherichia coli isolate Escherichia coli str. TO6

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2110925..2111028 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2110795..2111066 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECTO6_RS10345 2107350..2108012 - 663 WP_000944256.1 exodeoxyribonuclease X -
ECTO6_RS10350 2108036..2108692 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
ECTO6_RS10355 2108794..2109024 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ECTO6_RS10360 2109163..2109537 + 375 WP_000168747.1 CopC domain-containing protein YobA -
ECTO6_RS10365 2109541..2110413 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
ECTO6_RS10370 2110426..2110767 + 342 WP_000976476.1 YebY family protein -
- 2110795..2111066 - 272 - - Antitoxin
- 2110925..2111028 + 104 - - Toxin
ECTO6_RS10375 2111163..2111819 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
ECTO6_RS10380 2111820..2112011 - 192 WP_000457842.1 YebW family protein -
ECTO6_RS10385 2112116..2112352 - 237 WP_001295499.1 DUF1480 family protein -
ECTO6_RS10390 2112470..2113909 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T292709 NZ_LS992166:2110925-2111028 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT292709 NZ_LS992166:c2111066-2110795 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References