Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1951096..1951241 Replicon chromosome
Accession NZ_LR890616
Organism Klebsiella pneumoniae isolate INF359-sc-2280194

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1951132..1951234 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1951096..1951241 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX12_RS09420 1946226..1948286 + 2061 WP_004151449.1 oligopeptidase B -
JMX12_RS09425 1948290..1948949 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX12_RS09430 1949028..1949258 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX12_RS09435 1949371..1949745 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX12_RS09440 1949749..1950618 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMX12_RS09445 1950635..1950973 + 339 WP_002911404.1 YebY family protein -
- 1951096..1951241 - 146 - - Antitoxin
- 1951132..1951234 + 103 - - Toxin
JMX12_RS09450 1951609..1951752 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX12_RS09455 1951857..1952825 - 969 WP_074442383.1 VirK/YbjX family protein -
JMX12_RS09460 1952982..1953635 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
JMX12_RS09465 1953632..1953823 - 192 WP_002911395.1 YebW family protein -
JMX12_RS09470 1953921..1954160 - 240 WP_002911393.1 YebV family protein -
JMX12_RS09475 1954276..1955709 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291581 NZ_LR890616:1951132-1951234 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291581 NZ_LR890616:c1951241-1951096 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References