Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1951096..1951241 | Replicon | chromosome |
| Accession | NZ_LR890616 | ||
| Organism | Klebsiella pneumoniae isolate INF359-sc-2280194 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1951132..1951234 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1951096..1951241 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMX12_RS09420 | 1946226..1948286 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| JMX12_RS09425 | 1948290..1948949 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JMX12_RS09430 | 1949028..1949258 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMX12_RS09435 | 1949371..1949745 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JMX12_RS09440 | 1949749..1950618 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| JMX12_RS09445 | 1950635..1950973 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1951096..1951241 | - | 146 | - | - | Antitoxin |
| - | 1951132..1951234 | + | 103 | - | - | Toxin |
| JMX12_RS09450 | 1951609..1951752 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JMX12_RS09455 | 1951857..1952825 | - | 969 | WP_074442383.1 | VirK/YbjX family protein | - |
| JMX12_RS09460 | 1952982..1953635 | + | 654 | WP_024622748.1 | protein-serine/threonine phosphatase | - |
| JMX12_RS09465 | 1953632..1953823 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JMX12_RS09470 | 1953921..1954160 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JMX12_RS09475 | 1954276..1955709 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T291581 NZ_LR890616:1951132-1951234 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT291581 NZ_LR890616:c1951241-1951096 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT