Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1891080..1891225 Replicon chromosome
Accession NZ_LR890474
Organism Klebsiella pneumoniae isolate INF358-sc-2280191

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1891116..1891218 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1891080..1891225 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX23_RS09160 1886210..1888270 + 2061 WP_004151449.1 oligopeptidase B -
JMX23_RS09165 1888274..1888933 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX23_RS09170 1889012..1889242 - 231 WP_102024692.1 DNA polymerase III subunit theta -
JMX23_RS09175 1889355..1889729 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX23_RS09180 1889733..1890602 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
JMX23_RS09185 1890619..1890957 + 339 WP_002911404.1 YebY family protein -
- 1891080..1891225 - 146 - - Antitoxin
- 1891116..1891218 + 103 - - Toxin
JMX23_RS09190 1891593..1891736 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX23_RS09195 1891841..1892809 - 969 WP_004151446.1 VirK/YbjX family protein -
JMX23_RS09200 1892966..1893619 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
JMX23_RS09205 1893616..1893807 - 192 WP_002911395.1 YebW family protein -
JMX23_RS09210 1893905..1894144 - 240 WP_002911393.1 YebV family protein -
JMX23_RS09215 1894260..1895693 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291141 NZ_LR890474:1891116-1891218 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291141 NZ_LR890474:c1891225-1891080 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References