Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3607864..3608009 Replicon chromosome
Accession NZ_LR890471
Organism Klebsiella pneumoniae isolate INF168-sc-2280023

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3607871..3607973 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3607864..3608009 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX14_RS17560 3603396..3604829 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
JMX14_RS17565 3604945..3605184 + 240 WP_002911393.1 YebV family protein -
JMX14_RS17570 3605282..3605473 + 192 WP_002911395.1 YebW family protein -
JMX14_RS17575 3605470..3606123 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
JMX14_RS17580 3606280..3607248 + 969 WP_014907334.1 VirK/YbjX family protein -
JMX14_RS17585 3607353..3607496 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3607864..3608009 + 146 - - Antitoxin
- 3607871..3607973 - 103 - - Toxin
JMX14_RS17590 3608132..3608470 - 339 WP_002911404.1 YebY family protein -
JMX14_RS17595 3608487..3609356 - 870 WP_201519884.1 copper homeostasis membrane protein CopD -
JMX14_RS17600 3609360..3609734 - 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX14_RS17605 3609847..3610077 + 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX14_RS17610 3610156..3610815 + 660 WP_002911407.1 exodeoxyribonuclease X -
JMX14_RS17615 3610819..3612879 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T291126 NZ_LR890471:c3607973-3607871 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT291126 NZ_LR890471:3607864-3608009 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References