Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1984697..1984842 | Replicon | chromosome |
| Accession | NZ_LR890446 | ||
| Organism | Klebsiella pneumoniae isolate INF171-sc-2280028 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1984733..1984835 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1984697..1984842 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW80_RS09610 | 1979827..1981887 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| JMW80_RS09615 | 1981891..1982550 | - | 660 | WP_021440386.1 | exodeoxyribonuclease X | - |
| JMW80_RS09620 | 1982629..1982859 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMW80_RS09625 | 1982972..1983346 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JMW80_RS09630 | 1983350..1984219 | + | 870 | WP_021440385.1 | copper homeostasis membrane protein CopD | - |
| JMW80_RS09635 | 1984236..1984574 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1984697..1984842 | - | 146 | - | - | Antitoxin |
| - | 1984733..1984835 | + | 103 | - | - | Toxin |
| JMW80_RS09640 | 1985211..1985354 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JMW80_RS09645 | 1985459..1986427 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| JMW80_RS09650 | 1986584..1987237 | + | 654 | WP_021440384.1 | protein-serine/threonine phosphatase | - |
| JMW80_RS09655 | 1987234..1987425 | - | 192 | WP_073511300.1 | YebW family protein | - |
| JMW80_RS09660 | 1987523..1987762 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JMW80_RS09665 | 1987878..1989311 | - | 1434 | WP_021440382.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T291025 NZ_LR890446:1984733-1984835 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT291025 NZ_LR890446:c1984842-1984697 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
