Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1935267..1935412 | Replicon | chromosome |
| Accession | NZ_LR890374 | ||
| Organism | Klebsiella pneumoniae isolate INF250-sc-2280154 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1935303..1935405 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1935267..1935412 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW58_RS09455 | 1930397..1932457 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| JMW58_RS09460 | 1932461..1933120 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| JMW58_RS09465 | 1933199..1933429 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| JMW58_RS09470 | 1933542..1933916 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| JMW58_RS09475 | 1933920..1934789 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| JMW58_RS09480 | 1934806..1935144 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 1935267..1935412 | - | 146 | - | - | Antitoxin |
| - | 1935303..1935405 | + | 103 | - | - | Toxin |
| JMW58_RS09485 | 1935780..1935923 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| JMW58_RS09490 | 1936028..1936996 | - | 969 | WP_014907334.1 | VirK/YbjX family protein | - |
| JMW58_RS09495 | 1937153..1937806 | + | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| JMW58_RS09500 | 1937803..1937994 | - | 192 | WP_002911395.1 | YebW family protein | - |
| JMW58_RS09505 | 1938092..1938331 | - | 240 | WP_002911393.1 | YebV family protein | - |
| JMW58_RS09510 | 1938447..1939880 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T290806 NZ_LR890374:1935303-1935405 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT290806 NZ_LR890374:c1935412-1935267 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
