Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1842525..1842670 Replicon chromosome
Accession NZ_LR890317
Organism Klebsiella pneumoniae isolate INF215-sc-2280087

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1842561..1842663 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1842525..1842670 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMX39_RS09010 1837655..1839715 + 2061 WP_004151449.1 oligopeptidase B -
JMX39_RS09015 1839719..1840378 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMX39_RS09020 1840457..1840687 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMX39_RS09025 1840800..1841174 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMX39_RS09030 1841178..1842047 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMX39_RS09035 1842064..1842402 + 339 WP_002911404.1 YebY family protein -
- 1842525..1842670 - 146 - - Antitoxin
- 1842561..1842663 + 103 - - Toxin
JMX39_RS09040 1843039..1843182 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMX39_RS09045 1843287..1844255 - 969 WP_004151446.1 VirK/YbjX family protein -
JMX39_RS09050 1844412..1845065 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
JMX39_RS09055 1845062..1845253 - 192 WP_002911395.1 YebW family protein -
JMX39_RS09060 1845351..1845590 - 240 WP_002911393.1 YebV family protein -
JMX39_RS09065 1845706..1847139 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290616 NZ_LR890317:1842561-1842663 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290616 NZ_LR890317:c1842670-1842525 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References