Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1841449..1841594 Replicon chromosome
Accession NZ_LR890235
Organism Klebsiella pneumoniae isolate INF334-sc-2280143

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1841485..1841587 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1841449..1841594 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMV98_RS08850 1836579..1838639 + 2061 WP_004151449.1 oligopeptidase B -
JMV98_RS08855 1838643..1839302 - 660 WP_002911407.1 exodeoxyribonuclease X -
JMV98_RS08860 1839381..1839611 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JMV98_RS08865 1839724..1840098 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JMV98_RS08870 1840102..1840971 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
JMV98_RS08875 1840988..1841326 + 339 WP_002911404.1 YebY family protein -
- 1841449..1841594 - 146 - - Antitoxin
- 1841485..1841587 + 103 - - Toxin
JMV98_RS08880 1841962..1842105 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JMV98_RS08885 1842210..1843178 - 969 WP_004151446.1 VirK/YbjX family protein -
JMV98_RS08890 1843335..1843988 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
JMV98_RS08895 1843985..1844176 - 192 WP_002911395.1 YebW family protein -
JMV98_RS08900 1844274..1844513 - 240 WP_002911393.1 YebV family protein -
JMV98_RS08905 1844629..1846062 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T290359 NZ_LR890235:1841485-1841587 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT290359 NZ_LR890235:c1841594-1841449 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References