Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2215299..2215570 Replicon chromosome
Accession NZ_LR882997
Organism Escherichia coli isolate L3_E36_ETEC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2215429..2215532 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2215299..2215570 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL022_RS10890 2211854..2212516 - 663 WP_000944256.1 exodeoxyribonuclease X -
JL022_RS10895 2212540..2213196 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
JL022_RS10900 2213298..2213528 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JL022_RS10905 2213667..2214041 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JL022_RS10910 2214045..2214917 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
JL022_RS10915 2214930..2215271 + 342 WP_000976492.1 YebY family protein -
- 2215299..2215570 - 272 - - Antitoxin
- 2215429..2215532 + 104 - - Toxin
JL022_RS10920 2215667..2216323 + 657 WP_000812723.1 protein-serine/threonine phosphatase -
JL022_RS10925 2216324..2216515 - 192 WP_001338167.1 YebW family protein -
JL022_RS10930 2216620..2216856 - 237 WP_001295499.1 DUF1480 family protein -
JL022_RS10935 2216974..2218413 - 1440 WP_001352399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2138557..2231410 92853


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T290066 NZ_LR882997:2215429-2215532 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT290066 NZ_LR882997:c2215570-2215299 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References