Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2822035..2822512 Replicon chromosome
Accession NZ_LR882950
Organism Planktothrix agardhii strain PCC7805

Toxin (Protein)


Gene name - Uniprot ID A0A1J1JEC9
Locus tag NMG85_RS12875 Protein ID WP_042155864.1
Coordinates 2822240..2822512 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1J1JHM1
Locus tag NMG85_RS12870 Protein ID WP_042155865.1
Coordinates 2822035..2822259 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMG85_RS12830 (PCC7805_02576) 2817066..2817542 - 477 WP_042155870.1 R3H domain-containing nucleic acid-binding protein -
NMG85_RS12835 (PCC7805_02577) 2817545..2818702 - 1158 WP_042155869.1 membrane protein insertase YidC -
NMG85_RS12840 (PCC7805_02578) 2818848..2819240 - 393 WP_227364941.1 PH domain-containing protein -
NMG85_RS12845 (PCC7805_02579) 2819212..2819616 - 405 WP_042155868.1 ribonuclease P protein component -
NMG85_RS12850 (PCC7805_02580) 2819726..2819863 - 138 WP_071783091.1 50S ribosomal protein L34 -
NMG85_RS12855 (PCC7805_02581) 2819980..2820489 - 510 WP_026797999.1 DUF2808 domain-containing protein -
NMG85_RS12860 (PCC7805_02582) 2820637..2821281 - 645 WP_042155867.1 Uma2 family endonuclease -
NMG85_RS12865 (PCC7805_02583) 2821472..2821813 - 342 WP_235752153.1 DUF433 domain-containing protein -
NMG85_RS12870 (PCC7805_02584) 2822035..2822259 - 225 WP_042155865.1 CopG family antitoxin Antitoxin
NMG85_RS12875 (PCC7805_02585) 2822240..2822512 - 273 WP_042155864.1 BrnT family toxin Toxin
NMG85_RS12880 (PCC7805_02587) 2823571..2825661 + 2091 WP_235751906.1 DUF4352 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(3-68)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10918.26 Da        Isoelectric Point: 7.2018

>T289976 WP_042155864.1 NZ_LR882950:c2822512-2822240 [Planktothrix agardhii]
MYSFEYDDNKSRTNQQKHGIDFIEAQQLWQDDDLLEIQATSETESRFLAIGKLKQKHWTAVITYRLENIRIISVRRSRPN
EVIWYESRRI

Download         Length: 273 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8689.84 Da        Isoelectric Point: 4.4633

>AT289976 WP_042155865.1 NZ_LR882950:c2822259-2822035 [Planktothrix agardhii]
MKAEEFDAKFDTGEDLTEFMDFSTARRPNREKQKIELNLPLWMIRQLEAEAQKQGISPQTFLENYLAENLAPVR

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J1JEC9

Antitoxin

Source ID Structure
AlphaFold DB A0A1J1JHM1

References