Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2162114..2162591 Replicon chromosome
Accession NZ_LR882934
Organism Planktothrix agardhii strain NIVA-CYA126/8

Toxin (Protein)


Gene name - Uniprot ID A0A1J1JEC9
Locus tag NMK38_RS09910 Protein ID WP_042155864.1
Coordinates 2162319..2162591 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1J1JHM1
Locus tag NMK38_RS09905 Protein ID WP_042155865.1
Coordinates 2162114..2162338 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMK38_RS09870 (NIVACYA_01969) 2157467..2157943 - 477 WP_042155870.1 R3H domain-containing nucleic acid-binding protein -
NMK38_RS09875 (NIVACYA_01970) 2157946..2159103 - 1158 WP_042155869.1 membrane protein insertase YidC -
NMK38_RS09880 (NIVACYA_01971) 2159249..2159641 - 393 WP_026786219.1 PH domain-containing protein -
NMK38_RS09885 (NIVACYA_01972) 2159613..2160017 - 405 WP_042155868.1 ribonuclease P protein component -
NMK38_RS09890 (NIVACYA_01973) 2160127..2160264 - 138 WP_071783091.1 50S ribosomal protein L34 -
NMK38_RS09895 (NIVACYA_01974) 2160381..2160890 - 510 WP_026797999.1 DUF2808 domain-containing protein -
NMK38_RS09900 (NIVACYA_01975) 2161038..2161682 - 645 WP_042155867.1 Uma2 family endonuclease -
NMK38_RS09905 (NIVACYA_01977) 2162114..2162338 - 225 WP_042155865.1 CopG family antitoxin Antitoxin
NMK38_RS09910 (NIVACYA_01978) 2162319..2162591 - 273 WP_042155864.1 BrnT family toxin Toxin
NMK38_RS09915 2162915..2163079 + 165 WP_235751907.1 hypothetical protein -
NMK38_RS09920 2163265..2163483 - 219 Protein_1951 IS701 family transposase -
NMK38_RS09925 (NIVACYA_01980) 2163755..2166313 + 2559 WP_227351113.1 phosphoenolpyruvate--protein phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(3-68)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10918.26 Da        Isoelectric Point: 7.2018

>T289961 WP_042155864.1 NZ_LR882934:c2162591-2162319 [Planktothrix agardhii]
MYSFEYDDNKSRTNQQKHGIDFIEAQQLWQDDDLLEIQATSETESRFLAIGKLKQKHWTAVITYRLENIRIISVRRSRPN
EVIWYESRRI

Download         Length: 273 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8689.84 Da        Isoelectric Point: 4.4633

>AT289961 WP_042155865.1 NZ_LR882934:c2162338-2162114 [Planktothrix agardhii]
MKAEEFDAKFDTGEDLTEFMDFSTARRPNREKQKIELNLPLWMIRQLEAEAQKQGISPQTFLENYLAENLAPVR

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J1JEC9

Antitoxin

Source ID Structure
AlphaFold DB A0A1J1JHM1

References