Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1944896..1945041 Replicon chromosome
Accession NZ_LR745042
Organism Klebsiella pneumoniae isolate Klebsiella pneumoniae kpn154

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1944932..1945034 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1944896..1945041 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GW691_RS09450 1940026..1942086 + 2061 WP_004151449.1 oligopeptidase B -
GW691_RS09455 1942090..1942749 - 660 WP_002911407.1 exodeoxyribonuclease X -
GW691_RS09460 1942828..1943058 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GW691_RS09465 1943171..1943545 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GW691_RS09470 1943549..1944418 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
GW691_RS09475 1944435..1944773 + 339 WP_002911404.1 YebY family protein -
- 1944896..1945041 - 146 - - Antitoxin
- 1944932..1945034 + 103 - - Toxin
GW691_RS09480 1945408..1945551 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GW691_RS09485 1945656..1946624 - 969 WP_004151446.1 VirK/YbjX family protein -
GW691_RS09490 1946781..1947434 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
GW691_RS09495 1947431..1947622 - 192 WP_002911395.1 YebW family protein -
GW691_RS09500 1947720..1947959 - 240 WP_002911393.1 YebV family protein -
GW691_RS09505 1948075..1949508 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T289026 NZ_LR745042:1944932-1945034 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT289026 NZ_LR745042:c1945041-1944896 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References