Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 665271..665935 Replicon chromosome
Accession NZ_LR699009
Organism Pluralibacter gergoviae isolate MGYG-HGUT-02520

Toxin (Protein)


Gene name mqsR Uniprot ID A0A1S2B9G4
Locus tag FYC31_RS03115 Protein ID WP_048254840.1
Coordinates 665675..665935 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A1S2BC90
Locus tag FYC31_RS03110 Protein ID WP_048254841.1
Coordinates 665271..665672 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYC31_RS03085 660376..660636 - 261 WP_043081604.1 Sec-independent protein translocase subunit TatA -
FYC31_RS03090 660711..662351 - 1641 WP_048254845.1 ubiquinone biosynthesis regulatory protein kinase UbiB -
FYC31_RS03095 662348..662953 - 606 WP_045289365.1 SCP2 domain-containing protein -
FYC31_RS03100 662966..663721 - 756 WP_043081601.1 bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE -
FYC31_RS03105 663797..665200 - 1404 WP_048254843.1 DNA recombination protein RmuC -
FYC31_RS03110 665271..665672 - 402 WP_048254841.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FYC31_RS03115 665675..665935 - 261 WP_048254840.1 type II toxin-antitoxin system MqsR family toxin Toxin
FYC31_RS03120 666109..666870 - 762 WP_043081598.1 uridine phosphorylase -
FYC31_RS03125 667125..667934 + 810 WP_048254837.1 dienelactone hydrolase family protein -
FYC31_RS03130 667977..669929 - 1953 WP_053075608.1 glycoside hydrolase family 3 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-85)

Antitoxin

Zinc finger, MqsA-type

(3-48)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 9824.42 Da        Isoelectric Point: 10.4380

>T288753 WP_048254840.1 NZ_LR699009:c665935-665675 [Pluralibacter gergoviae]
MVSQGKLRVTANAFDGAALLGFSFPLAVSIASLINSLKPYDFYKSRTAYHDRTIWHDVYRVGRHQRQIYLKLIVQGDVLI
VSLKER

Download         Length: 261 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 15065.02 Da        Isoelectric Point: 6.2316

>AT288753 WP_048254841.1 NZ_LR699009:c665672-665271 [Pluralibacter gergoviae]
MKCPFCGSSVLKTETRDVIRAYKDQNTTIYALTGDFCDACGEILLDGEEGDRYARHMHDFRKSVNASEVDPAFIAAVRRR
LNLDQRQAAEFFGGGVNAFSRYETGKVAPPRPLVLLFKDFDKHPELFDELRQA

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S2B9G4

Antitoxin

Source ID Structure
AlphaFold DB A0A1S2BC90

References