Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4161708..4162404 Replicon chromosome
Accession NZ_LR699008
Organism Hafnia alvei isolate MGYG-HGUT-02508

Toxin (Protein)


Gene name mqsR Uniprot ID A0A4Q9EV19
Locus tag FYB81_RS18970 Protein ID WP_043489473.1
Coordinates 4162093..4162404 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag FYB81_RS18965 Protein ID WP_043489471.1
Coordinates 4161708..4162106 (-) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYB81_RS18955 4157404..4159851 + 2448 WP_025799360.1 glycogen phosphorylase -
FYB81_RS18960 4159981..4161465 - 1485 WP_025799362.1 glycerol-3-phosphate dehydrogenase -
FYB81_RS18965 4161708..4162106 - 399 WP_043489471.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FYB81_RS18970 4162093..4162404 - 312 WP_043489473.1 type II toxin-antitoxin system MqsR family toxin Toxin
FYB81_RS18975 4162660..4163418 - 759 WP_025799366.1 DeoR/GlpR family transcriptional regulator -
FYB81_RS18980 4163465..4164301 - 837 WP_043489475.1 rhomboid family intramembrane serine protease GlpG -
FYB81_RS18985 4164349..4164678 - 330 WP_025799370.1 thiosulfate sulfurtransferase GlpE -
FYB81_RS18990 4164952..4165383 + 432 WP_043489478.1 hypothetical protein -
FYB81_RS18995 4165519..4166277 - 759 WP_025799373.1 glycerophosphodiester phosphodiesterase -
FYB81_RS19000 4166311..4167387 - 1077 WP_111330657.1 sn-glycerol-3-phosphate import ATP-binding protein UgpC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA

(3-131)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 12053.05 Da        Isoelectric Point: 8.2604

>T288751 WP_043489473.1 NZ_LR699008:c4162404-4162093 [Hafnia alvei]
MEKRTPHCSLEKVRNLIGKGMIKATKVAYLNAKRLDFSCADMYRVVSELSAKDFYKSMTTYQNHKIWQDVYHCHLEKVSL
YLKLTVVDEVLIVSFKELDDDMS

Download         Length: 312 bp

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14872.07 Da        Isoelectric Point: 4.9755

>AT288751 WP_043489471.1 NZ_LR699008:c4162106-4161708 [Hafnia alvei]
MICPECGSSNTVKEYRDTPYTYKGQTMIIKAWGADWCLDCGEGVIFKEESLRIDSILTEFNKQVNASIIDPEYVVAMRKK
LNLSQSEAGEIFGGGVNAFSRYETGKALPHVSTIKLLKLLDKYPELLEEIRN

Download         Length: 399 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4Q9EV19

Antitoxin

Source ID Structure

References