Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEi(antitoxin) |
| Location | 206817..207639 | Replicon | chromosome |
| Accession | NZ_LR698969 | ||
| Organism | Murdochiella vaginalis isolate MGYG-HGUT-01563 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | - |
| Locus tag | FXY30_RS07580 | Protein ID | WP_071704944.1 |
| Coordinates | 207445..207639 (+) | Length | 65 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | - |
| Locus tag | FXY30_RS00855 | Protein ID | WP_071704943.1 |
| Coordinates | 206817..207452 (+) | Length | 212 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FXY30_RS00840 | 201912..203300 | - | 1389 | WP_071704941.1 | FAD-dependent oxidoreductase | - |
| FXY30_RS07525 | 203594..203764 | - | 171 | WP_157885016.1 | hypothetical protein | - |
| FXY30_RS00845 | 204057..205067 | + | 1011 | WP_071704942.1 | LacI family transcriptional regulator | - |
| FXY30_RS00850 | 205080..206747 | + | 1668 | WP_083428128.1 | hypothetical protein | - |
| FXY30_RS00855 | 206817..207452 | + | 636 | WP_071704943.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| FXY30_RS07580 | 207445..207639 | + | 195 | WP_071704944.1 | hypothetical protein | Toxin |
| FXY30_RS00865 | 208007..210751 | + | 2745 | WP_071704945.1 | cation-translocating P-type ATPase | - |
| FXY30_RS00870 | 210831..211328 | + | 498 | WP_071704946.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| FXY30_RS00875 | 211456..212172 | + | 717 | WP_071704947.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7323.61 Da Isoelectric Point: 6.9724
>T288697 WP_071704944.1 NZ_LR698969:207445-207639 [Murdochiella vaginalis]
MNKANVLALCHKVEQKTGLSFNTVLLYYFLESILKRLTDGENKDSFRQMVSLDIAMVDVITPLF
MNKANVLALCHKVEQKTGLSFNTVLLYYFLESILKRLTDGENKDSFRQMVSLDIAMVDVITPLF
Download Length: 195 bp
Antitoxin
Download Length: 212 a.a. Molecular weight: 24415.95 Da Isoelectric Point: 9.5356
>AT288697 WP_071704943.1 NZ_LR698969:206817-207452 [Murdochiella vaginalis]
MVLFPCDNNKRRKKSNYQSKIESYLQKNNGLISSSYCKSRGIPTVYLTRLHRRGKLLRLTKGLYGLPDGGYDELFVFQHR
YKSTIFSYETALFLLGESDRIPQSIDVTVANSYKFNEPPANLLIHYVDPKIISLGVQSVQTMFGNSVKAYSYERVLCDFI
ANKDKVDAESYVKTIQGYAKYQNRDVHHLWEIAHALGIENRVRNILELIYE
MVLFPCDNNKRRKKSNYQSKIESYLQKNNGLISSSYCKSRGIPTVYLTRLHRRGKLLRLTKGLYGLPDGGYDELFVFQHR
YKSTIFSYETALFLLGESDRIPQSIDVTVANSYKFNEPPANLLIHYVDPKIISLGVQSVQTMFGNSVKAYSYERVLCDFI
ANKDKVDAESYVKTIQGYAKYQNRDVHHLWEIAHALGIENRVRNILELIYE
Download Length: 636 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|