Detailed information of TA system TA288634

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2904017..2904918
• Replicon: chromosome
• Accession: NZ_LR595855
• Organism: Raoultella terrigena strain NCTC9189

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FQU09_RS14055
• Protein ID: WP_143967148.1
• Coordinates: 2904457..2904918 (+)
• Length: 154 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: FQU09_RS14050
• Protein ID: WP_115192780.1
• Coordinates: 2904017..2904460 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FQU09_RS14030	2900041..2900940	-	900	WP_143967145.1	LysR family transcriptional regulator	-
FQU09_RS14035	2901208..2902419	+	1212	WP_143967146.1	SMP-30/gluconolactonase/LRE family protein	-
FQU09_RS14040	2902497..2903126	-	630	WP_143967147.1	TetR/AcrR family transcriptional regulator	-
FQU09_RS14045	2903164..2903877	+	714	WP_041145501.1	SDR family oxidoreductase	-
FQU09_RS14050	2904017..2904460	+	444	WP_115192780.1	DUF2384 domain-containing protein	Antitoxin
FQU09_RS14055	2904457..2904918	+	462	WP_143967148.1	RES family NAD+ phosphorylase	Toxin
FQU09_RS14060	2904969..2905214	-	246	WP_041145498.1	YmjA family protein	-
FQU09_RS14065	2905389..2905880	-	492	WP_045855351.1	GNAT family N-acetyltransferase	-
FQU09_RS14070	2905976..2906653	-	678	WP_143967944.1	transporter substrate-binding domain-containing protein	-
FQU09_RS14075	2906899..2907414	+	516	WP_143967945.1	hypothetical protein	-
FQU09_RS14080	2907459..2908742	-	1284	WP_041145496.1	citrate synthase	-
FQU09_RS14085	2908916..2909632	-	717	WP_041145495.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (32-89)

Sequences

Toxin

Protein

• Length: 154 a.a.
• Molecular weight: 16880.27 Da
• Isoelectric Point: 5.7283

>T288634 WP_143967148.1 NZ_LR595855:2904457-2904918 [Raoultella terrigena]
VILYRLTKSRFLTTAWSGFGAKEAGGRWNSVGTAMVYLSEAASLTMLETLVHINAPQLLDDFTLLSIDVPDDQVLTVDPA
SLPADWAREDAPARLARYGDEWAARAASAALRVPSALSPVEYNYLFNPQHPAVFDLLASVKRIPFRFDTRLKA

Nucleotide

• Length: 462 bp

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16337.60 Da
• Isoelectric Point: 6.7345

>AT288634 WP_115192780.1 NZ_LR595855:2904017-2904460 [Raoultella terrigena]
MKVYSPTENAEKNLSPWHAIGLDAEDGIALMGKISHGLEGSVARQISAWAEITPAELRKMSGIANTTFNRSIKSRFSADQ
SERLVRILRVIERAVELFEGDKEAAQKWMNEPNRALGWKTPAEVVSSETGALEVMRLITRVEHGVYS

Nucleotide

• Length: 444 bp