Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2339449..2339683 Replicon chromosome
Accession NZ_LR213458
Organism Shigella sonnei strain AUSMDU00008333 isolate AUSMDU00008333

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2339579..2339682 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2339449..2339683 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E0E38_RS11590 2336004..2336666 - 663 WP_000944256.1 exodeoxyribonuclease X -
E0E38_RS11595 2336690..2337346 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
E0E38_RS11600 2337448..2337678 - 231 WP_000916763.1 DNA polymerase III subunit theta -
E0E38_RS11605 2337817..2338191 + 375 WP_000168735.1 CopC domain-containing protein YobA -
E0E38_RS11610 2338195..2339067 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
E0E38_RS11615 2339080..2339421 + 342 WP_000976476.1 YebY family protein -
- 2339449..2339683 - 235 - - Antitoxin
- 2339579..2339682 + 104 - - Toxin
E0E38_RS11620 2339814..2340890 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
E0E38_RS11625 2340927..2341172 - 246 Protein_2229 IS1 family transposase -
E0E38_RS11640 2342553..2343308 - 756 WP_001282649.1 IS21-like element ISSso4 family helper ATPase IstB -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - ipaH9.8 2333947..2356682 22735


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T288296 NZ_LR213458:2339579-2339682 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT288296 NZ_LR213458:c2339683-2339449 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References