Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 1949301..1949535 | Replicon | chromosome |
| Accession | NZ_LR213452 | ||
| Organism | Shigella flexneri strain AUSMDU00008355 isolate AUSMDU00008355 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 1949431..1949534 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 1949301..1949535 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E0E33_RS09985 | 1945856..1946518 | - | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
| E0E33_RS09990 | 1946542..1947198 | - | 657 | Protein_1898 | carbon-nitrogen hydrolase family protein | - |
| E0E33_RS09995 | 1947300..1947530 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| E0E33_RS10000 | 1947669..1948043 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| E0E33_RS10005 | 1948047..1948919 | + | 873 | Protein_1901 | copper homeostasis membrane protein CopD | - |
| E0E33_RS10010 | 1948932..1949273 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 1949301..1949535 | - | 235 | - | - | Antitoxin |
| - | 1949431..1949534 | + | 104 | - | - | Toxin |
| E0E33_RS10015 | 1949666..1950742 | - | 1077 | Protein_1903 | phage integrase Arm DNA-binding domain-containing protein | - |
| E0E33_RS10020 | 1950708..1950989 | - | 282 | WP_005127484.1 | excisionase | - |
| E0E33_RS10025 | 1951106..1951954 | - | 849 | Protein_1905 | IS3-like element IS600 family transposase | - |
| E0E33_RS10030 | 1952009..1953218 | + | 1210 | Protein_1906 | IS3 family transposase | - |
| E0E33_RS10035 | 1953261..1953571 | - | 311 | Protein_1907 | transposase | - |
| E0E33_RS10040 | 1953635..1954102 | + | 468 | Protein_1908 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T288245 NZ_LR213452:1949431-1949534 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT288245 NZ_LR213452:c1949535-1949301 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
