Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 979714..980408 Replicon chromosome
Accession NZ_LR134373
Organism Yersinia pseudotuberculosis strain NCTC10275

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag EL213_RS04235 Protein ID WP_024063131.1
Coordinates 979714..980010 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID Q666X1
Locus tag EL213_RS04240 Protein ID WP_002209924.1
Coordinates 980010..980408 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL213_RS04205 974836..976353 + 1518 WP_002209930.1 lysine--tRNA ligase -
EL213_RS04215 976786..978000 + 1215 WP_011192954.1 tyrosine-type recombinase/integrase -
EL213_RS04220 978082..978267 - 186 WP_002209928.1 hypothetical protein -
EL213_RS04225 978865..979125 + 261 WP_002214785.1 type II toxin-antitoxin system RelE/ParE family toxin -
EL213_RS04230 979188..979550 + 363 WP_011192920.1 helix-turn-helix domain-containing protein -
EL213_RS04235 979714..980010 + 297 WP_024063131.1 type II toxin-antitoxin system MqsR family toxin Toxin
EL213_RS04240 980010..980408 + 399 WP_002209924.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EL213_RS04245 980808..983099 - 2292 WP_024063132.1 toprim domain-containing protein -
EL213_RS04250 983399..983725 + 327 WP_002209922.1 type II toxin-antitoxin system RelE/ParE family toxin -
EL213_RS21250 983718..983870 + 153 WP_002209921.1 hypothetical protein -
EL213_RS04255 983884..984084 - 201 WP_002209920.1 AlpA family transcriptional regulator -
EL213_RS04260 984266..984922 - 657 WP_024063133.1 hypothetical protein -
EL213_RS04265 984935..985300 - 366 WP_011192915.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(75-128)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11318.17 Da        Isoelectric Point: 7.8810

>T287822 WP_024063131.1 NZ_LR134373:979714-980010 [Yersinia pseudotuberculosis]
MEKRTPHTRLLKVKELVLKGNIKTTRTARDGAEELGLSFRDMCDAVSELISADFYKSMTTHQDHTIWQDVYRPMLSCGRV
YLKITVIDDVLIVSFKEI

Download         Length: 297 bp

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14657.17 Da        Isoelectric Point: 8.4923

>AT287822 WP_002209924.1 NZ_LR134373:980010-980408 [Yersinia pseudotuberculosis]
MMKCPVCGGVELIHEARDVPFTYKGRKFIVEGVIGQHCPACGETVMTEAESDVYAAKTMLLRKMVNTESIAPAYIVQIRK
KLGLNQREASEIFGGGVNAFSRYEKGKALPHPSTIKLLQVLDKHPELLNEIR

Download         Length: 399 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q666X1

References