Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3223019..3223546 Replicon chromosome
Accession NZ_LR134335
Organism Yersinia enterocolitica subsp. palearctica strain NCTC13769

Toxin (Protein)


Gene name relE Uniprot ID A0A7T9XW08
Locus tag EL202_RS15340 Protein ID WP_005166250.1
Coordinates 3223271..3223546 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7T9XW39
Locus tag EL202_RS15335 Protein ID WP_005166251.1
Coordinates 3223019..3223267 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL202_RS15310 3219619..3220713 + 1095 WP_005166255.1 LPS export ABC transporter permease LptF -
EL202_RS15315 3220713..3221783 + 1071 WP_005166254.1 LPS export ABC transporter permease LptG -
EL202_RS15325 3222080..3222588 - 509 Protein_2879 helix-turn-helix domain containing protein -
EL202_RS15330 3222649..3222942 + 294 Protein_2880 DUF4942 domain-containing protein -
EL202_RS15335 3223019..3223267 + 249 WP_005166251.1 ribbon-helix-helix domain-containing protein Antitoxin
EL202_RS15340 3223271..3223546 + 276 WP_005166250.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL202_RS15345 3223665..3224453 + 789 WP_005166249.1 helix-turn-helix domain-containing protein -
EL202_RS15350 3224681..3224812 + 132 Protein_2884 IS3 family transposase -
EL202_RS15355 3224866..3225591 - 726 WP_005180647.1 IS21-like element ISYen2A/ISYen2B family helper ATPase IstB -
EL202_RS15360 3225578..3227086 - 1509 WP_005180650.1 IS21-like element ISYen2A family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-42)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10974.31 Da        Isoelectric Point: 4.5486

>T287736 WP_005166250.1 NZ_LR134335:3223271-3223546 [Yersinia enterocolitica subsp. palearctica]
MEIYWTLKAQDDLERIYCFALQYSRQHGDDVLDRLITGCAGLTAYPAIGVQQTRYEPREVRKVLFDDYEVHYELRDNDIY
IVDLWHTKEER

Download         Length: 276 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9034.30 Da        Isoelectric Point: 6.4624

>AT287736 WP_005166251.1 NZ_LR134335:3223019-3223267 [Yersinia enterocolitica subsp. palearctica]
MGSLTKQTISAQIPVELATAVENLAIELDRSKSWIIKEALTSMLAERERRHQSIQAGLADVDAGRVVSHSDMVDFANRLK
QS

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T9XW08

Antitoxin

Source ID Structure
AlphaFold DB A0A7T9XW39

References