Detailed information of TA system TA287669

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mosAT/AbiEii-AbiEi
• Location: 1308784..1310500
• Replicon: chromosome
• Accession: NZ_LR134321
• Organism: Shewanella baltica strain NCTC10737

Toxin (Protein)

• Gene name: mosT
• Uniprot ID: -
• Locus tag: EL185_RS05725
• Protein ID: WP_126491403.1
• Coordinates: 1309565..1310500 (+)
• Length: 312 a.a.

Antitoxin (Protein)

• Gene name: mosA
• Uniprot ID: -
• Locus tag: EL185_RS05720
• Protein ID: WP_126491402.1
• Coordinates: 1308784..1309572 (+)
• Length: 263 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EL185_RS05695	1304953..1305897	+	945	WP_126491398.1	viperin family antiviral radical SAM protein	-
EL185_RS05700	1305907..1306227	+	321	WP_126491399.1	hypothetical protein	-
EL185_RS05705	1306603..1307391	+	789	WP_126491400.1	trypsin-like serine protease	-
EL185_RS05710	1307503..1307883	+	381	WP_126491401.1	DUF952 domain-containing protein	-
EL185_RS05715	1308131..1308529	-	399	WP_012089073.1	hypothetical protein	-
EL185_RS05720	1308784..1309572	+	789	WP_126491402.1	type IV toxin-antitoxin system AbiEi family antitoxin	Antitoxin
EL185_RS05725	1309565..1310500	+	936	WP_126491403.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
EL185_RS05730	1310620..1311030	-	411	WP_106649807.1	hypothetical protein	-
EL185_RS05735	1311067..1311324	-	258	WP_107404660.1	hypothetical protein	-
EL185_RS05740	1311442..1312902	-	1461	WP_126491404.1	site-specific integrase	-
EL185_RS05745	1313091..1313477	+	387	WP_126491405.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1283112..1314007	30895

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (13-266)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (1-97)

Sequences

Toxin

Protein

• Length: 312 a.a.
• Molecular weight: 35317.09 Da
• Isoelectric Point: 6.7660

>T287669 WP_126491403.1 NZ_LR134321:1309565-1310500 [Shewanella baltica]
MNKSSIYYQQVSLLIRMLPLVAQEKVFALKGGTAINLFVRNFPRLSVDIDLAYLPLEPREQALQSVKEALGRLTAQINLQ
PNLSAVFQDNKYDELRVVVTSDRVTIKIEVSPVARGTLHKAVLMPVVELVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVKMLLAEEGISREILVGFLTYTLSHPRPINEVMSPRWKPLDESFQTEFNGMTTKPIKLDELVLTRSEMLTALQH
HFTAKDRDFLLSFKQGQPDWSLFDEPSVAALPAVRWKLLNIQNLAKNKSKHQEQLIKLADVLETWVAGRIL

Nucleotide

• Length: 936 bp

Antitoxin

Protein

• Length: 263 a.a.
• Molecular weight: 29884.96 Da
• Isoelectric Point: 9.3615

>AT287669 WP_126491402.1 NZ_LR134321:1308784-1309572 [Shewanella baltica]
MSSKINWLINHTSPGAVVLQSWLTQNEISSSLVRKYVQSGWLYKISAGVYVRPESTGKLQPHWVEALKAVNEQLKLPVHL
AGVSSLTHQGLSHYLQLSSEQVWVGCQSKQALPKWFRELEEQNWLFYTSSKLTQTLEKDFITIGVNNREVKASCAELAAY
EVVNAIGKHISFEHAAELFQGLVNLSPRKIQSILNRSESVQANRVFLFLGHYYQHQWSKRLDEQQITLGAGKRQVVAHGR
YDGRYQITVPASFIKTEENQYE

Nucleotide

• Length: 789 bp