Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1516200..1516900 Replicon chromosome
Accession NZ_LR134189
Organism Providencia rustigianii strain NCTC6933

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL059_RS06900 Protein ID WP_126436699.1
Coordinates 1516200..1516571 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D1NZL2
Locus tag EL059_RS06905 Protein ID WP_006813433.1
Coordinates 1516580..1516900 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL059_RS06880 1511419..1512045 + 627 WP_164717602.1 protein phosphatase CheZ -
EL059_RS06885 1512197..1512545 - 349 Protein_1327 HNH nuclease YajD -
EL059_RS06890 1512817..1513967 + 1151 Protein_1328 flagellar type III secretion system protein FlhB -
EL059_RS06895 1513960..1516058 + 2099 Protein_1329 flagellar biosynthesis protein FlhA -
EL059_RS06900 1516200..1516571 + 372 WP_126436699.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EL059_RS06905 1516580..1516900 + 321 WP_006813433.1 helix-turn-helix domain-containing protein Antitoxin
EL059_RS06910 1516938..1517378 - 441 WP_006813432.1 flagellar export chaperone FlgN -
EL059_RS06915 1517390..1517693 - 304 Protein_1333 anti-sigma-28 factor FlgM -
EL059_RS06920 1517904..1518571 - 668 Protein_1334 flagellar basal body P-ring formation protein FlgA -
EL059_RS06925 1518803..1519216 + 414 WP_126436701.1 flagellar basal body rod protein FlgB -
EL059_RS06930 1519222..1519626 + 405 WP_006813426.1 flagellar basal body rod protein FlgC -
EL059_RS06935 1519639..1520496 + 858 WP_115164158.1 flagellar basal-body rod modification protein -
EL059_RS06940 1520527..1521795 + 1269 WP_006813424.1 flagellar hook protein FlgE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-119)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-95)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13962.41 Da        Isoelectric Point: 10.2396

>T286968 WP_126436699.1 NZ_LR134189:1516200-1516571 [Providencia rustigianii]
MAIYKTKIFKSKLKKLELDEIDVLLAAKQVLSGCYEADLGGGVIKKRLAIQGFGKRAGIRTIIFYKQGSHLFFADGWSKS
RLASKGRKEIEDDDLESYKDIARILLNSDPIKIAHMLKNWLFN

Download         Length: 372 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12111.11 Da        Isoelectric Point: 9.7949

>AT286968 WP_006813433.1 NZ_LR134189:1516580-1516900 [Providencia rustigianii]
MSNTMKELLEFAQGLEKIGVTDDIASRRIEARIKARELKEKFSALKPMTGEDIKRIREENNISQSSLALILNMTKESVSK
WERDEIKPNGAALRLLNLIEQKTLII

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB D1NZL2

References