Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1219641..1220335 Replicon chromosome
Accession NZ_LR134161
Organism Yersinia enterocolitica subsp. enterocolitica strain NCTC13629

Toxin (Protein)


Gene name mqsR Uniprot ID A0A7U7FJ92
Locus tag EL026_RS05560 Protein ID WP_005166025.1
Coordinates 1219641..1219937 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A7U7IQA2
Locus tag EL026_RS05565 Protein ID WP_005166024.1
Coordinates 1219937..1220335 (+) Length 133 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL026_RS05525 1215114..1216212 + 1099 WP_020282590.1 peptide chain release factor 2 -
EL026_RS05530 1216222..1217739 + 1518 WP_005166031.1 lysine--tRNA ligase -
EL026_RS05550 1218796..1219056 + 261 WP_005166028.1 type II toxin-antitoxin system RelE/ParE family toxin -
EL026_RS05555 1219122..1219484 + 363 WP_005166026.1 helix-turn-helix domain-containing protein -
EL026_RS05560 1219641..1219937 + 297 WP_005166025.1 type II toxin-antitoxin system MqsR family toxin Toxin
EL026_RS05565 1219937..1220335 + 399 WP_005166024.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
EL026_RS05570 1220442..1221644 - 1203 WP_005177049.1 IS256 family transposase -
EL026_RS05575 1221793..1221993 - 201 WP_005166614.1 AlpA family transcriptional regulator -
EL026_RS05580 1222011..1222847 + 837 Protein_1036 Fic family protein -
EL026_RS05585 1223219..1223614 + 396 WP_005166615.1 SgcJ/EcaC family oxidoreductase -
EL026_RS05590 1223697..1224941 + 1245 WP_005166619.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(75-128)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11322.18 Da        Isoelectric Point: 7.7766

>T286908 WP_005166025.1 NZ_LR134161:1219641-1219937 [Yersinia enterocolitica subsp. enterocolitica]
MEKRTPHTRLLKVKELVLKGNVKSTRTARDGAEELGLSFRDMCDVVCELTSADFYKSMTTHQDHTIWQDVYRPMLSCGRV
YLKITVIDDVLIVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 133 a.a.        Molecular weight: 14716.19 Da        Isoelectric Point: 8.8165

>AT286908 WP_005166024.1 NZ_LR134161:1219937-1220335 [Yersinia enterocolitica subsp. enterocolitica]
MMKCPVCGGAELIHEARDVPFTYKGRKFIVEGVIGQHCPACGETIMTEAESDTYAAKTMLLRKMVNTESIAPAYIVQVRK
KLGLNQREASEIFGGGVNAFSRYEKGKALPHRSTIKLLQVLDKYPELLNEIR

Download         Length: 399 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7FJ92

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7IQA2

References