Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3107971..3108602 Replicon chromosome
Accession NZ_LR134151
Organism Serratia plymuthica strain NCTC8900

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EL066_RS14960 Protein ID WP_126483482.1
Coordinates 3107971..3108369 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EL066_RS14965 Protein ID WP_126483484.1
Coordinates 3108369..3108602 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL066_RS14935 3103489..3103875 + 387 WP_197718809.1 type II toxin-antitoxin system RelE/ParE family toxin -
EL066_RS14940 3103856..3104158 + 303 WP_126483474.1 transcriptional regulator -
EL066_RS14945 3104216..3104620 - 405 WP_126483476.1 flagellar protein FlhE -
EL066_RS14950 3104620..3106698 - 2079 WP_126483478.1 flagellar biosynthesis protein FlhA -
EL066_RS14955 3106691..3107842 - 1152 WP_126483480.1 flagellar type III secretion system protein FlhB -
EL066_RS14960 3107971..3108369 - 399 WP_126483482.1 type II toxin-antitoxin system VapC family toxin Toxin
EL066_RS14965 3108369..3108602 - 234 WP_126483484.1 antitoxin Antitoxin
EL066_RS14970 3108726..3109370 - 645 WP_126483486.1 protein phosphatase CheZ -
EL066_RS14975 3109381..3109770 - 390 WP_006321484.1 chemotaxis response regulator CheY -
EL066_RS14980 3109991..3111040 - 1050 WP_126483488.1 chemotaxis response regulator protein-glutamate methylesterase -
EL066_RS14985 3111040..3111912 - 873 WP_126483490.1 protein-glutamate O-methyltransferase CheR -
EL066_RS14990 3111941..3113566 - 1626 WP_126483492.1 Tar ligand binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-45)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14852.98 Da        Isoelectric Point: 7.5219

>T286869 WP_126483482.1 NZ_LR134151:c3108369-3107971 [Serratia plymuthica]
MFSHMLDTNIVIYVIKRRPIEVLSKFNQHAGKMVISSVTYAELIHGVEKSARPTENARVVDDFVSRLEILDYSAKAAAHY
GNIRASLEQQGTPIGVNDLHIAGHARSEGLVLVTNNLREFERVDGLRLQNWL

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8851.89 Da        Isoelectric Point: 5.0642

>AT286869 WP_126483484.1 NZ_LR134151:c3108602-3108369 [Serratia plymuthica]
MTLGSVFTNNRTQAVRLPAEVRFPDSVSKVTVRVVGKERILAPVENTWDSFFCTDKHASDDFLTERAEQYQPERESF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References