Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 499997..500568 Replicon chromosome
Accession NZ_LR134151
Organism Serratia plymuthica strain NCTC8900

Toxin (Protein)


Gene name relE Uniprot ID A0A7U3YYL5
Locus tag EL066_RS02360 Protein ID WP_013811308.1
Coordinates 500293..500568 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EL066_RS02355 Protein ID WP_126479918.1
Coordinates 499997..500284 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL066_RS02330 495699..496784 - 1086 WP_126479909.1 carbon-phosphorus lyase complex subunit PhnI -
EL066_RS02335 496784..497365 - 582 WP_126479910.1 phosphonate C-P lyase system protein PhnH -
EL066_RS02340 497369..497812 - 444 WP_126479912.1 phosphonate C-P lyase system protein PhnG -
EL066_RS02345 497813..498538 - 726 WP_172603393.1 phosphonate metabolism transcriptional regulator PhnF -
EL066_RS02350 498833..499891 + 1059 WP_126479916.1 permease -
EL066_RS02355 499997..500284 + 288 WP_126479918.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EL066_RS02360 500293..500568 + 276 WP_013811308.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
EL066_RS02365 500572..501036 - 465 WP_126479920.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
EL066_RS02370 501205..503343 - 2139 WP_126479922.1 anaerobic ribonucleoside-triphosphate reductase -
EL066_RS02375 503558..504463 - 906 WP_126479924.1 LysR family transcriptional regulator -
EL066_RS02380 504568..505092 + 525 WP_126479926.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10712.50 Da        Isoelectric Point: 9.6236

>T286857 WP_013811308.1 NZ_LR134151:500293-500568 [Serratia plymuthica]
MRIEWDNAALRDRERIFEFLYIFNPQAAVQADNEIDKAVKRLLEHPELGKTWHGKARKLLINKASLLLVYIIVDDVIKVF
AIAHQREKFPN

Download         Length: 276 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11087.41 Da        Isoelectric Point: 5.8001

>AT286857 WP_126479918.1 NZ_LR134151:499997-500284 [Serratia plymuthica]
MESRIQFRIEDETKRLAQKAAEAKGTTLSEACRRLAEQMADEQRAAEEHENWLKDKVDAAFSRLHEGNAVYLNQQEVEES
MDVFKAKIRAKYDRK

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U3YYL5

Antitoxin

Source ID Structure

References