Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 210925..211398 Replicon chromosome
Accession NZ_LR134151
Organism Serratia plymuthica strain NCTC8900

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EL066_RS00960 Protein ID WP_063202450.1
Coordinates 211123..211398 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2X4TR66
Locus tag EL066_RS00955 Protein ID WP_062869225.1
Coordinates 210925..211122 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL066_RS00930 206365..207636 + 1272 WP_126486211.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
EL066_RS00935 207633..208832 + 1200 WP_126479654.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
EL066_RS00940 208880..209443 - 564 WP_126479655.1 DcrB family lipoprotein -
EL066_RS00945 209733..210398 - 666 WP_126479656.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
EL066_RS00950 210619..210864 + 246 WP_004950955.1 sulfurtransferase TusA -
EL066_RS00955 210925..211122 + 198 WP_062869225.1 hypothetical protein Antitoxin
EL066_RS00960 211123..211398 + 276 WP_063202450.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
EL066_RS00965 211458..213773 - 2316 WP_126479657.1 zinc/cadmium/mercury/lead-transporting ATPase -
EL066_RS00970 214467..215930 + 1464 WP_126479658.1 serralysin family metalloprotease -
EL066_RS00975 215986..216363 + 378 WP_126479659.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10660.56 Da        Isoelectric Point: 11.2606

>T286856 WP_063202450.1 NZ_LR134151:211123-211398 [Serratia plymuthica]
MLVIEWSRSARQDLADILLFIANDNPRAARKMKVLISEAILPAAEHPHIFRRGRVDGTHEIIVHPNYLLIYQVVADRIRV
MRVLHARRRYP

Download         Length: 276 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7580.65 Da        Isoelectric Point: 4.4488

>AT286856 WP_062869225.1 NZ_LR134151:210925-211122 [Serratia plymuthica]
MVILRSPVVSEYETQEQTEIYDRWFREKVREAMDDPLPGISHDEVMAEMDALIAVAEARKKTKQV

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2X4TR66

References