Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2529154..2529338 Replicon chromosome
Accession NZ_LR134085
Organism Staphylococcus aureus strain NCTC12233

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag ELZ52_RS13335 Protein ID WP_000482650.1
Coordinates 2529231..2529338 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2529154..2529214 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELZ52_RS13310 2524685..2524852 - 168 WP_001790576.1 hypothetical protein -
ELZ52_RS13320 2525083..2526816 - 1734 WP_000486494.1 ABC transporter ATP-binding protein/permease -
ELZ52_RS13325 2526841..2528604 - 1764 WP_001064838.1 ABC transporter ATP-binding protein/permease -
ELZ52_RS13335 2529231..2529338 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
ELZ52_RS13340 2529472..2529858 - 387 WP_000779358.1 flippase GtxA -
ELZ52_RS13345 2530126..2531268 + 1143 WP_001176863.1 glycerate kinase -
ELZ52_RS13350 2531328..2531987 + 660 WP_000831298.1 membrane protein -
ELZ52_RS13355 2532169..2533380 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
ELZ52_RS13360 2533503..2533976 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T286699 WP_000482650.1 NZ_LR134085:c2529338-2529231 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT286699 NZ_LR134085:2529154-2529214 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References