Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 702908..703571 Replicon chromosome
Accession NZ_LR133996
Organism Shimwellia blattae strain NCTC10965

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EL017_RS03365 Protein ID WP_002444974.1
Coordinates 703155..703571 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID I2B5K8
Locus tag EL017_RS03360 Protein ID WP_002444972.1
Coordinates 702908..703174 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EL017_RS03340 698740..699327 + 588 WP_002444964.1 HD domain-containing protein -
EL017_RS03345 699366..700094 + 729 WP_014715822.1 MurR/RpiR family transcriptional regulator -
EL017_RS03350 700230..701663 + 1434 WP_002444968.1 6-phospho-beta-glucosidase -
EL017_RS03355 701696..702685 - 990 WP_002444970.1 tRNA-modifying protein YgfZ -
EL017_RS03360 702908..703174 + 267 WP_002444972.1 FAD assembly factor SdhE Antitoxin
EL017_RS03365 703155..703571 + 417 WP_002444974.1 hypothetical protein Toxin
EL017_RS03370 703586..704107 - 522 WP_002444975.1 flavodoxin FldB -
EL017_RS03375 704243..705127 + 885 WP_126348978.1 site-specific tyrosine recombinase XerD -
EL017_RS03380 705157..705873 + 717 WP_002444979.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
EL017_RS03385 705877..707610 + 1734 WP_002444982.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16236.11 Da        Isoelectric Point: 11.2011

>T286547 WP_002444974.1 NZ_LR133996:703155-703571 [Shimwellia blattae]
VVLWQSELRVSWRAQWLSLLLHGIVAAVVLLLPWPLNYLPVWLLLLSLVVLDCVRSQRRINARHGEIKLLDNSQLHWLGR
DWLILGTPWMSRAGMLLRLRDTTTARRHLLWVASDSVDQGEWRDLRRVLAEQKYQPPH

Download         Length: 417 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10390.84 Da        Isoelectric Point: 5.9602

>AT286547 WP_002444972.1 NZ_LR133996:702908-703174 [Shimwellia blattae]
MDINNKARIHWACRRGMRELDISIMPFFEHDYDTLSDDEKHTFVRLLACDDPDLFNWLMNHGKPADADLQHMIALIQQRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I2B5K8

References